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Myocardial TGFβ2 Is Required for Atrioventricular Cushion Remodeling and Myocardial Development

Among the three transforming growth factor beta (TGFβ) ligands, TGFβ2 is essential for heart development and is produced by multiple cell types, including myocardium. Heterozygous mutations in TGFB2 in patients of connective tissue disorders result in congenital heart defects and adult valve malform...

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Detalles Bibliográficos
Autores principales: Bhattacharya, Aniket, Al-Sammarraie, Nadia, Gebere, Mengistu G., Johnson, John, Eberth, John F., Azhar, Mohamad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7999251/
https://www.ncbi.nlm.nih.gov/pubmed/33801433
http://dx.doi.org/10.3390/jcdd8030026