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Myocardial TGFβ2 Is Required for Atrioventricular Cushion Remodeling and Myocardial Development
Among the three transforming growth factor beta (TGFβ) ligands, TGFβ2 is essential for heart development and is produced by multiple cell types, including myocardium. Heterozygous mutations in TGFB2 in patients of connective tissue disorders result in congenital heart defects and adult valve malform...
Autores principales: | Bhattacharya, Aniket, Al-Sammarraie, Nadia, Gebere, Mengistu G., Johnson, John, Eberth, John F., Azhar, Mohamad |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7999251/ https://www.ncbi.nlm.nih.gov/pubmed/33801433 http://dx.doi.org/10.3390/jcdd8030026 |
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