Cargando…
Transcriptome Analysis Reveals the AhR, Smad2/3, and HIF-1α Pathways as the Mechanism of Ochratoxin A Toxicity in Kidney Cells
Ochratoxin A (OTA) is a mycotoxin occurring in foods consumed by humans. Recently, there has been growing global concern regarding OTA toxicity. The main target organ of OTA is the kidney, but the mechanism underlying renal toxicity is not well known. In this study, human-derived proximal tubular ep...
Autores principales: | Pyo, Min Cheol, Choi, In-Geol, Lee, Kwang-Won |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7999264/ https://www.ncbi.nlm.nih.gov/pubmed/33800744 http://dx.doi.org/10.3390/toxins13030190 |
Ejemplares similares
-
Ochratoxin A-Induced Hepatotoxicity through Phase I and Phase II Reactions Regulated by AhR in Liver Cells
por: Shin, Hye Soo, et al.
Publicado: (2019) -
AhR and HIF-1α Signaling Pathways in Benign Meningioma under Hypoxia
por: Perepechaeva, Maria L., et al.
Publicado: (2023) -
The Landscape of AhR Regulators and Coregulators to Fine-Tune AhR Functions
por: Gargaro, Marco, et al.
Publicado: (2021) -
Ochratoxin A induces endoplasmic reticulum stress and fibrosis in the kidney via the HIF-1α/miR-155-5p link
por: Yang, Seon Ah, et al.
Publicado: (2023) -
Interaction between AhR and HIF-1 signaling pathways mediated by ARNT/HIF-1β
por: Zhang, Mengdi, et al.
Publicado: (2022)