Cargando…
Assessment of Two Novel Live-Attenuated Vaccine Candidates for Herpes Simplex Virus 2 (HSV-2) in Guinea Pigs
Treatment to ameliorate the symptoms of infection with herpes simplex virus 2 (HSV-2) and to suppress reactivation has been available for decades. However, a safe and effective preventative or therapeutic vaccine has eluded development. Two novel live-attenuated HSV-2 vaccine candidates (RVx201 and...
Autores principales: | Joyce, Jonathan D., Patel, Anant K., Murphy, Brandie, Carr, Daniel J.J., Gershburg, Edward, Bertke, Andrea S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7999511/ https://www.ncbi.nlm.nih.gov/pubmed/33805768 http://dx.doi.org/10.3390/vaccines9030258 |
Ejemplares similares
-
Pan-HSV-2 IgG Antibody in Vaccinated Mice and Guinea Pigs Correlates with Protection against Herpes Simplex Virus 2
por: Halford, William P., et al.
Publicado: (2013) -
Herpes Simplex Virus 2 (HSV-2) Infected Cell Proteins Are among the Most Dominant Antigens of a Live-Attenuated HSV-2 Vaccine
por: Geltz, Joshua J., et al.
Publicado: (2015) -
Virus-Specific Immune Memory at Peripheral Sites of Herpes Simplex Virus Type 2 (HSV-2) Infection in Guinea Pigs
por: Xia, Jingya, et al.
Publicado: (2014) -
Immunization with a dominant-negative recombinant Herpes Simplex Virus (HSV) type 1 protects against HSV-2 genital disease in guinea pigs
por: Brans, Richard, et al.
Publicado: (2010) -
An Adenovirus-Based Recombinant Herpes Simplex Virus 2 (HSV-2) Therapeutic Vaccine Is Highly Protective against Acute and Recurrent HSV-2 Disease in a Guinea Pig Model
por: Wan, Mingming, et al.
Publicado: (2023)