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Lessons, Challenges and Future Therapeutic Opportunities for PI3K Inhibition in CLL
SIMPLE SUMMARY: The phosphoinositide 3-kinase (PI3K) is a family of kinases that play a key role in the biology of chronic lymphocytic leukemia (CLL). Inhibitors of PI3K demonstrated efficacy in the treatment of CLL, associated with significant adverse events that limited the clinical use of this dr...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7999552/ https://www.ncbi.nlm.nih.gov/pubmed/33805745 http://dx.doi.org/10.3390/cancers13061280 |