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Lessons, Challenges and Future Therapeutic Opportunities for PI3K Inhibition in CLL

SIMPLE SUMMARY: The phosphoinositide 3-kinase (PI3K) is a family of kinases that play a key role in the biology of chronic lymphocytic leukemia (CLL). Inhibitors of PI3K demonstrated efficacy in the treatment of CLL, associated with significant adverse events that limited the clinical use of this dr...

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Detalles Bibliográficos
Autores principales:	Guarente, Valerio, Sportoletti, Paolo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7999552/ https://www.ncbi.nlm.nih.gov/pubmed/33805745 http://dx.doi.org/10.3390/cancers13061280

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