Cargando…

Immunogenicity and Safety of an Inactivated SARS-CoV-2 Vaccine: Preclinical Studies

Since the emergence of SARS-CoV-2 at the end of 2019, 64 candidate vaccines are in clinical development and 173 are in the pre-clinical phase. Five types of vaccines are currently approved for emergency use in many countries (Inactivated, Sinopharm; Viral-vector, Astrazeneca, and Gamaleya Research I...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kandeil, Ahmed, Mostafa, Ahmed, Hegazy, Rehab R., El-Shesheny, Rabeh, El Taweel, Ahmed, Gomaa, Mokhtar R., Shehata, Mahmoud, Elbaset, Marawan A., Kayed, Ahmed E., Mahmoud, Sara H., Moatasim, Yassmin, Kutkat, Omnia, Yassen, Noha N., Shabana, Marwa E., GabAllah, Mohamed, Kamel, Mina Nabil, Abo Shama, Noura M., El Sayes, Mohamed, Ahmed, Amira N., Elalfy, Zahraa S., Mohamed, Bassim MSA, Abd El-Fattah, Safa N., El Hariri, Hazem Mohamed, Abdel Kader, Mona, Azmy, Osama, Kayali, Ghazi, Ali, Mohamed A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7999656/ https://www.ncbi.nlm.nih.gov/pubmed/33802467 http://dx.doi.org/10.3390/vaccines9030214

Ejemplares similares

Impact of Individual Viral Gene Segments from Influenza A/H5N8 Virus on the Protective Efficacy of Inactivated Subtype-Specific Influenza Vaccine
por: Moatasim, Yassmin, et al.
Publicado: (2021)

Comparative pathogenic potential of avian influenza H7N3 viruses isolated from wild birds in Egypt and their sensitivity to commercial antiviral drugs
por: Kayed, Ahmed E., et al.
Publicado: (2023)

Potent Antiviral Activity of Vitamin B12 against Severe Acute Respiratory Syndrome Coronavirus 2, Middle East Respiratory Syndrome Coronavirus, and Human Coronavirus 229E
por: Moatasim, Yassmin, et al.
Publicado: (2023)

FDA-Approved Drugs with Potent In Vitro Antiviral Activity against Severe Acute Respiratory Syndrome Coronavirus 2
por: Mostafa, Ahmed, et al.
Publicado: (2020)

Incidence, household transmission, and neutralizing antibody seroprevalence of Coronavirus Disease 2019 in Egypt: Results of a community-based cohort
por: Gomaa, Mokhtar R., et al.
Publicado: (2021)

Common childhood vaccines do not elicit a cross-reactive antibody response against SARS-CoV-2
por: Kandeil, Ahmed, et al.
Publicado: (2020)

Insights into Genetic Characteristics and Virological Features of Endemic Avian Influenza A (H9N2) Viruses in Egypt from 2017–2021
por: El Sayes, Mohamed, et al.
Publicado: (2022)

Bioactive Polyphenolic Compounds Showing Strong Antiviral Activities against Severe Acute Respiratory Syndrome Coronavirus 2
por: Kandeil, Ahmed, et al.
Publicado: (2021)

Coding-Complete Genome Sequences of Two SARS-CoV-2 Isolates from Egypt
por: Kandeil, Ahmed, et al.
Publicado: (2020)

Genetic and Antigenic Characteristics of Highly Pathogenic Avian Influenza A(H5N8) Viruses Circulating in Domestic Poultry in Egypt, 2017–2021
por: Kandeil, Ahmed, et al.
Publicado: (2022)

In Vitro and In Vivo Antiviral Studies of New Heteroannulated 1,2,3-Triazole Glycosides Targeting the Neuraminidase of Influenza A Viruses
por: Kutkat, Omnia, et al.
Publicado: (2022)

Systematic, active surveillance for Middle East respiratory syndrome coronavirus in camels in Egypt
por: Ali, Mohamed A, et al.
Publicado: (2017)

Robust antiviral activity of commonly prescribed antidepressants against emerging coronaviruses: in vitro and in silico drug repurposing studies
por: Kutkat, Omnia, et al.
Publicado: (2022)

Prevalence of Severe Acute Respiratory Syndrome Coronavirus 2 Neutralizing Antibodies in Egyptian Convalescent Plasma Donors
por: Gomaa, Mokhtar R., et al.
Publicado: (2020)

Highly Pathogenic Avian Influenza A(H5N1) Virus Clade 2.3.4.4b in Wild Birds and Live Bird Markets, Egypt
por: El-Shesheny, Rabeh, et al.
Publicado: (2022)

We are underestimating, again, the true burden of H5N1 in humans
por: Gomaa, Mokhtar, et al.
Publicado: (2023)

Comparative Virological and Pathogenic Characteristics of Avian Influenza H5N8 Viruses Detected in Wild Birds and Domestic Poultry in Egypt during the Winter of 2016/2017
por: Moatasim, Yassmin, et al.
Publicado: (2019)

Determinants of having severe acute respiratory syndrome coronavirus 2 neutralizing antibodies in Egypt
por: El Rifay, Amira S., et al.
Publicado: (2021)

Active surveillance and genetic evolution of avian influenza viruses in Egypt, 2016–2018
por: Kandeil, Ahmed, et al.
Publicado: (2019)

Middle East respiratory syndrome coronavirus infection in non-camelid domestic mammals
por: Kandeil, Ahmed, et al.
Publicado: (2019)

Active Surveillance for Avian Influenza Virus, Egypt, 2010–2012
por: Kayali, Ghazi, et al.
Publicado: (2014)

Middle East Respiratory Syndrome Coronavirus (MERS-CoV): State of the Science
por: Mostafa, Ahmed, et al.
Publicado: (2020)

Complete Genome Sequence of Middle East Respiratory Syndrome Coronavirus Isolated from a Dromedary Camel in Egypt
por: Kandeil, Ahmed, et al.
Publicado: (2016)

Induced humoral immunity of different types of vaccines against most common variants of SARS-CoV-2 in Egypt prior to Omicron outbreak
por: El-Shesheny, Rabeh, et al.
Publicado: (2022)

Surveillance for avian influenza viruses in wild birds at live bird markets, Egypt, 2014‐2016
por: Kayed, Ahmed S., et al.
Publicado: (2019)

A Recombinant Influenza A/H1N1 Carrying A Short Immunogenic Peptide of MERS-CoV as Bivalent Vaccine in BALB/c Mice
por: Shehata, Mahmoud M., et al.
Publicado: (2019)

Scrutinizing the Feasibility of Nonionic Surfactants to Form Isotropic Bicelles of Curcumin: a Potential Antiviral Candidate Against COVID-19
por: Mahmoud, Dina B., et al.
Publicado: (2021)

Evolution of H5-Type Avian Influenza A Virus Towards Mammalian Tropism in Egypt, 2014 to 2015
por: Mahmoud, Sara Hussein, et al.
Publicado: (2019)

Delineating a potent antiviral activity of Cuphea ignea extract loaded nano-formulation against SARS-CoV-2: In silico and in vitro studies
por: Mahmoud, Dina B., et al.
Publicado: (2021)

Design and statistical optimisation of emulsomal nanoparticles for improved anti-SARS-CoV-2 activity of N-(5-nitrothiazol-2-yl)-carboxamido candidates: in vitro and in silico studies
por: Al-Karmalawy, Ahmed A., et al.
Publicado: (2023)

PA from a Recent H9N2 (G1-Like) Avian Influenza A Virus (AIV) Strain Carrying Lysine 367 Confers Altered Replication Efficiency and Pathogenicity to Contemporaneous H5N1 in Mammalian Systems
por: Mostafa, Ahmed, et al.
Publicado: (2020)

3-Alkenyl-2-oxindoles: Synthesis, antiproliferative and antiviral properties against SARS-CoV-2
por: Girgis, Adel S., et al.
Publicado: (2021)

Whole-Genome Sequence of a Human Monkeypox Virus Strain Detected in Egypt
por: Roshdy, Wael H., et al.
Publicado: (2023)

Avian Influenza A(H5N1) Virus in Egypt
por: Kayali, Ghazi, et al.
Publicado: (2016)

EGYVIR: An immunomodulatory herbal extract with potent antiviral activity against SARS-CoV-2
por: Roshdy, Wael H., et al.
Publicado: (2020)

Immunogenicity and effectiveness of a bivalent influenza A/H1N2 vaccine strain against seasonal human influenza A viruses in mice
por: Kamel, Mina Nabil, et al.
Publicado: (2022)

Discovery of novel thioquinazoline-N-aryl-acetamide/N-arylacetohydrazide hybrids as anti-SARS-CoV-2 agents: Synthesis, in vitro biological evaluation, and molecular docking studies
por: Abdel-Mohsen, Heba T., et al.
Publicado: (2023)

Diversity of Astroviruses Circulating in Humans, Bats, and Wild Birds in Egypt
por: El Taweel, Ahmed, et al.
Publicado: (2020)

Continuing Threat of Influenza (H5N1) Virus Circulation in Egypt
por: Kayali, Ghazi, et al.
Publicado: (2011)

Incidence and seroprevalence of seasonal influenza a viruses in Egypt: Results of a community‐based cohort study
por: Gomaa, Mokhtar R., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_ilvh3eimt7i41i17aqcedse5a8