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SPECT/CT Correlation in the Diagnosis of Unilateral Condilar Hyperplasia

Objective: To evaluate the correlation between metabolic bone activity measured by single photon emission computed tomography (SPECT) and the anatomic condylar characteristics acquired by computed tomography (CT), in patients with unilateral condylar hyperplasia (UCH). Method and Materials/Patients:...

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Autores principales: López, Diego Fernando, Ríos Borrás, Valentina, Muñoz, Juan Manuel, Cardenas-Perilla, Rodrigo, Almeida, Luis Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7999681/
https://www.ncbi.nlm.nih.gov/pubmed/33800475
http://dx.doi.org/10.3390/diagnostics11030477
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author López, Diego Fernando
Ríos Borrás, Valentina
Muñoz, Juan Manuel
Cardenas-Perilla, Rodrigo
Almeida, Luis Eduardo
author_facet López, Diego Fernando
Ríos Borrás, Valentina
Muñoz, Juan Manuel
Cardenas-Perilla, Rodrigo
Almeida, Luis Eduardo
author_sort López, Diego Fernando
collection PubMed
description Objective: To evaluate the correlation between metabolic bone activity measured by single photon emission computed tomography (SPECT) and the anatomic condylar characteristics acquired by computed tomography (CT), in patients with unilateral condylar hyperplasia (UCH). Method and Materials/Patients: Observational, descriptive study in a group of 71 patients with clinical diagnosis of UCH and indication of SPECT/CT. Bone SPECT images obtained in a gamma-camera GE Infina and processed in a station Xeleris 3 with the program Volumetrix MI Evolution for bone. CT images acquired in a PET/CT Biograph mcT20 equipment (Siemens) processed in a station Osirix V 7.5.1 (Pixmeo, Bomex, Switzerland). Results: The sample included 24 men (33.8%) and 47 women (66.2%). Active state UCH was detected in 40 (56.3%) cases (over 55% uptake in the affected condyle) and 38 (53.5%) presented mandibular deviation to the right side. No significant differences related to sex, age, or mandibular deviation side were found. Mandibular deviation was the only morphologic feature related to active/inactive UCH (p = 0.003). The likelihood of active CH was significantly higher in patients with mandibular deviation higher than 6 mm compared with <6 mm (odds ratio (OR): 3.51, confidence interval (CI) 95%: 1.27–9.72). Conclusion: There is a significant correlation between the magnitude of mandibular deviation quantified on CT and metabolic findings obtained by SPECT in patients with UCH. The risk of active UCH is 3.5 times higher in patients with a mandibular deviation ≥6 mm.
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spelling pubmed-79996812021-03-28 SPECT/CT Correlation in the Diagnosis of Unilateral Condilar Hyperplasia López, Diego Fernando Ríos Borrás, Valentina Muñoz, Juan Manuel Cardenas-Perilla, Rodrigo Almeida, Luis Eduardo Diagnostics (Basel) Article Objective: To evaluate the correlation between metabolic bone activity measured by single photon emission computed tomography (SPECT) and the anatomic condylar characteristics acquired by computed tomography (CT), in patients with unilateral condylar hyperplasia (UCH). Method and Materials/Patients: Observational, descriptive study in a group of 71 patients with clinical diagnosis of UCH and indication of SPECT/CT. Bone SPECT images obtained in a gamma-camera GE Infina and processed in a station Xeleris 3 with the program Volumetrix MI Evolution for bone. CT images acquired in a PET/CT Biograph mcT20 equipment (Siemens) processed in a station Osirix V 7.5.1 (Pixmeo, Bomex, Switzerland). Results: The sample included 24 men (33.8%) and 47 women (66.2%). Active state UCH was detected in 40 (56.3%) cases (over 55% uptake in the affected condyle) and 38 (53.5%) presented mandibular deviation to the right side. No significant differences related to sex, age, or mandibular deviation side were found. Mandibular deviation was the only morphologic feature related to active/inactive UCH (p = 0.003). The likelihood of active CH was significantly higher in patients with mandibular deviation higher than 6 mm compared with <6 mm (odds ratio (OR): 3.51, confidence interval (CI) 95%: 1.27–9.72). Conclusion: There is a significant correlation between the magnitude of mandibular deviation quantified on CT and metabolic findings obtained by SPECT in patients with UCH. The risk of active UCH is 3.5 times higher in patients with a mandibular deviation ≥6 mm. MDPI 2021-03-08 /pmc/articles/PMC7999681/ /pubmed/33800475 http://dx.doi.org/10.3390/diagnostics11030477 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ).
spellingShingle Article
López, Diego Fernando
Ríos Borrás, Valentina
Muñoz, Juan Manuel
Cardenas-Perilla, Rodrigo
Almeida, Luis Eduardo
SPECT/CT Correlation in the Diagnosis of Unilateral Condilar Hyperplasia
title SPECT/CT Correlation in the Diagnosis of Unilateral Condilar Hyperplasia
title_full SPECT/CT Correlation in the Diagnosis of Unilateral Condilar Hyperplasia
title_fullStr SPECT/CT Correlation in the Diagnosis of Unilateral Condilar Hyperplasia
title_full_unstemmed SPECT/CT Correlation in the Diagnosis of Unilateral Condilar Hyperplasia
title_short SPECT/CT Correlation in the Diagnosis of Unilateral Condilar Hyperplasia
title_sort spect/ct correlation in the diagnosis of unilateral condilar hyperplasia
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7999681/
https://www.ncbi.nlm.nih.gov/pubmed/33800475
http://dx.doi.org/10.3390/diagnostics11030477
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