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Downregulation of Mcl-1 by Panobinostat Potentiates Proton Beam Therapy in Hepatocellular Carcinoma Cells

Epigenetic modulation by histone deacetylase (HDAC) inhibitors is an attractive anti-cancer strategy for diverse hematological and solid cancers. Herein, we explored the relative effectiveness of the pan-HDAC inhibitor panobinostat in combination with proton over X-ray irradiation in HCC cells. Clon...

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Detalles Bibliográficos
Autores principales:	Choi, Changhoon, Lee, Ga Haeng, Son, Arang, Yoo, Gyu Sang, Yu, Jeong Il, Park, Hee Chul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7999709/ https://www.ncbi.nlm.nih.gov/pubmed/33806487 http://dx.doi.org/10.3390/cells10030554

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