Transcript Variants of Genes Involved in Neurodegeneration Are Differentially Regulated by the APOE and MAPT Haplotypes

Genetic variations at the Apolipoprotein E (ApoE) and microtubule-associated protein tau (MAPT) loci have been implicated in multiple neurogenerative diseases, but their exact molecular mechanisms are unclear. In this study, we performed transcript level linear modelling using the blood whole transc...

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Detalles Bibliográficos
Autores principales: Koks, Sulev, Pfaff, Abigail L., Bubb, Vivien J., Quinn, John P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7999745/
https://www.ncbi.nlm.nih.gov/pubmed/33804213
http://dx.doi.org/10.3390/genes12030423

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7999745/
https://www.ncbi.nlm.nih.gov/pubmed/33804213
http://dx.doi.org/10.3390/genes12030423

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