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SARS-CoV-2 Disease Adjuvant Therapies and Supplements Breakthrough for the Infection Prevention

The SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) is a high-risk viral agent involved in the recent pandemic stated worldwide by the World Health Organization. The infection is correlated to a severe systemic and respiratory disease in many cases, which is clinically treated with a mu...

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Autores principales: Inchingolo, Alessio Danilo, Inchingolo, Angelo Michele, Bordea, Ioana Roxana, Malcangi, Giuseppina, Xhajanka, Edit, Scarano, Antonio, Lorusso, Felice, Farronato, Marco, Tartaglia, Gianluca Martino, Isacco, Ciro Gargiulo, Marinelli, Grazia, D’Oria, Maria Teresa, Hazballa, Denisa, Santacroce, Luigi, Ballini, Andrea, Contaldo, Maria, Inchingolo, Francesco, Dipalma, Gianna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7999785/
https://www.ncbi.nlm.nih.gov/pubmed/33806624
http://dx.doi.org/10.3390/microorganisms9030525
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author Inchingolo, Alessio Danilo
Inchingolo, Angelo Michele
Bordea, Ioana Roxana
Malcangi, Giuseppina
Xhajanka, Edit
Scarano, Antonio
Lorusso, Felice
Farronato, Marco
Tartaglia, Gianluca Martino
Isacco, Ciro Gargiulo
Marinelli, Grazia
D’Oria, Maria Teresa
Hazballa, Denisa
Santacroce, Luigi
Ballini, Andrea
Contaldo, Maria
Inchingolo, Francesco
Dipalma, Gianna
author_facet Inchingolo, Alessio Danilo
Inchingolo, Angelo Michele
Bordea, Ioana Roxana
Malcangi, Giuseppina
Xhajanka, Edit
Scarano, Antonio
Lorusso, Felice
Farronato, Marco
Tartaglia, Gianluca Martino
Isacco, Ciro Gargiulo
Marinelli, Grazia
D’Oria, Maria Teresa
Hazballa, Denisa
Santacroce, Luigi
Ballini, Andrea
Contaldo, Maria
Inchingolo, Francesco
Dipalma, Gianna
author_sort Inchingolo, Alessio Danilo
collection PubMed
description The SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) is a high-risk viral agent involved in the recent pandemic stated worldwide by the World Health Organization. The infection is correlated to a severe systemic and respiratory disease in many cases, which is clinically treated with a multi-drug pharmacological approach. The purpose of this investigation was to evaluate through a literature overview the effect of adjuvant therapies and supplements for the SARS-CoV-2 infection. The research has analyzed the advantage of the EK1C4, by also assessing the studies on the resveratrol, vitamin D, and melatonin as adjuvant supplements for long hauler patients’ prognosis. The evaluated substances reported important benefits for the improvement of the immune system and as a potential inhibitor molecules against SARS-CoV-2, highlighting the use of sartans as therapy. The adjuvant supplements seem to create an advantage for the healing of the long hauler patients affected by chronic symptoms of constant chest and heart pain, intestinal disorders, headache, difficulty concentrating, memory loss, and tachycardia.
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spelling pubmed-79997852021-03-28 SARS-CoV-2 Disease Adjuvant Therapies and Supplements Breakthrough for the Infection Prevention Inchingolo, Alessio Danilo Inchingolo, Angelo Michele Bordea, Ioana Roxana Malcangi, Giuseppina Xhajanka, Edit Scarano, Antonio Lorusso, Felice Farronato, Marco Tartaglia, Gianluca Martino Isacco, Ciro Gargiulo Marinelli, Grazia D’Oria, Maria Teresa Hazballa, Denisa Santacroce, Luigi Ballini, Andrea Contaldo, Maria Inchingolo, Francesco Dipalma, Gianna Microorganisms Review The SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) is a high-risk viral agent involved in the recent pandemic stated worldwide by the World Health Organization. The infection is correlated to a severe systemic and respiratory disease in many cases, which is clinically treated with a multi-drug pharmacological approach. The purpose of this investigation was to evaluate through a literature overview the effect of adjuvant therapies and supplements for the SARS-CoV-2 infection. The research has analyzed the advantage of the EK1C4, by also assessing the studies on the resveratrol, vitamin D, and melatonin as adjuvant supplements for long hauler patients’ prognosis. The evaluated substances reported important benefits for the improvement of the immune system and as a potential inhibitor molecules against SARS-CoV-2, highlighting the use of sartans as therapy. The adjuvant supplements seem to create an advantage for the healing of the long hauler patients affected by chronic symptoms of constant chest and heart pain, intestinal disorders, headache, difficulty concentrating, memory loss, and tachycardia. MDPI 2021-03-04 /pmc/articles/PMC7999785/ /pubmed/33806624 http://dx.doi.org/10.3390/microorganisms9030525 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ).
spellingShingle Review
Inchingolo, Alessio Danilo
Inchingolo, Angelo Michele
Bordea, Ioana Roxana
Malcangi, Giuseppina
Xhajanka, Edit
Scarano, Antonio
Lorusso, Felice
Farronato, Marco
Tartaglia, Gianluca Martino
Isacco, Ciro Gargiulo
Marinelli, Grazia
D’Oria, Maria Teresa
Hazballa, Denisa
Santacroce, Luigi
Ballini, Andrea
Contaldo, Maria
Inchingolo, Francesco
Dipalma, Gianna
SARS-CoV-2 Disease Adjuvant Therapies and Supplements Breakthrough for the Infection Prevention
title SARS-CoV-2 Disease Adjuvant Therapies and Supplements Breakthrough for the Infection Prevention
title_full SARS-CoV-2 Disease Adjuvant Therapies and Supplements Breakthrough for the Infection Prevention
title_fullStr SARS-CoV-2 Disease Adjuvant Therapies and Supplements Breakthrough for the Infection Prevention
title_full_unstemmed SARS-CoV-2 Disease Adjuvant Therapies and Supplements Breakthrough for the Infection Prevention
title_short SARS-CoV-2 Disease Adjuvant Therapies and Supplements Breakthrough for the Infection Prevention
title_sort sars-cov-2 disease adjuvant therapies and supplements breakthrough for the infection prevention
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7999785/
https://www.ncbi.nlm.nih.gov/pubmed/33806624
http://dx.doi.org/10.3390/microorganisms9030525
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