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13R,20-Dihydroxydocosahexaenoic Acid, a Novel Dihydroxy- DHA Derivative, Inhibits Breast Cancer Stemness through Regulation of the Stat3/IL-6 Signaling Pathway by Inducing ROS Production

Breast cancer is a major health problem worldwide. Cancer stem cells (CSCs) are known to mediate breast cancer metastasis and recurrence and are therefore a promising therapeutic target. In this study, we investigated the anti-inflammatory effect of 13R,20-dihydroxydocosahexaenoic acid (13R,20-diHDH...

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Detalles Bibliográficos
Autores principales: Wang, Lifang, Choi, Hack Sun, Lee, Binna, Choi, Jong Hyun, Jang, Yong-Suk, Seo, Jeong-Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7999786/
https://www.ncbi.nlm.nih.gov/pubmed/33804152
http://dx.doi.org/10.3390/antiox10030457