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SARS-CoV-2 in Pregnancy—The First Wave

Background and Objectives: COVID-19, a disease caused by SARS-CoV-2, is a public health emergency. Data on the effect of the virus on pregnancy are limited. Materials and Methods: We carried out a retrospective descriptive study, in order to evaluate the obstetric results on pregnant women in which...

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Autores principales: de Vasconcelos Gaspar, Andreia, Santos Silva, Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7999825/
https://www.ncbi.nlm.nih.gov/pubmed/33807607
http://dx.doi.org/10.3390/medicina57030241
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author de Vasconcelos Gaspar, Andreia
Santos Silva, Isabel
author_facet de Vasconcelos Gaspar, Andreia
Santos Silva, Isabel
author_sort de Vasconcelos Gaspar, Andreia
collection PubMed
description Background and Objectives: COVID-19, a disease caused by SARS-CoV-2, is a public health emergency. Data on the effect of the virus on pregnancy are limited. Materials and Methods: We carried out a retrospective descriptive study, in order to evaluate the obstetric results on pregnant women in which SARS-CoV-2 was detected through RT-PCR of the nasopharyngeal swab, at admission to the maternity hospital. Results: From 16 March to 31 July 2020, 12 SARS-CoV-2 positive pregnant women have been hospitalized. Eleven were hospitalized for initiation or induction of labor, corresponding to 0.64% of deliveries in the maternity hospital. One pregnant woman was hospitalized for threatened abortion, culminating in a stillbirth at 20 weeks of gestation. Regarding the severity of the disease, nine women were asymptomatic and three had mild illness (two had associated cough and one headache). Three had relevant environmental exposure and a history of contact with infected persons. None had severe or critical illness due to SARS-CoV-2. There were no maternal deaths. The following gestational complications were observed: one stillbirth, one preterm labor, one preterm prelabor rupture of membranes, and one fetal growth restriction. Four deliveries were eutocic, two vacuum-assisted deliveries and five were cesarean sections. The indications for cesarean section were obstetric. Conclusions: SARS-CoV-2 infection was found in a minority of hospitalized pregnant women in this sample. Most are asymptomatic or have mild illness, from gestational complications to highlight stillbirth and preterm birth. There were no cases of vertical transmission by coronavirus.
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spelling pubmed-79998252021-03-28 SARS-CoV-2 in Pregnancy—The First Wave de Vasconcelos Gaspar, Andreia Santos Silva, Isabel Medicina (Kaunas) Article Background and Objectives: COVID-19, a disease caused by SARS-CoV-2, is a public health emergency. Data on the effect of the virus on pregnancy are limited. Materials and Methods: We carried out a retrospective descriptive study, in order to evaluate the obstetric results on pregnant women in which SARS-CoV-2 was detected through RT-PCR of the nasopharyngeal swab, at admission to the maternity hospital. Results: From 16 March to 31 July 2020, 12 SARS-CoV-2 positive pregnant women have been hospitalized. Eleven were hospitalized for initiation or induction of labor, corresponding to 0.64% of deliveries in the maternity hospital. One pregnant woman was hospitalized for threatened abortion, culminating in a stillbirth at 20 weeks of gestation. Regarding the severity of the disease, nine women were asymptomatic and three had mild illness (two had associated cough and one headache). Three had relevant environmental exposure and a history of contact with infected persons. None had severe or critical illness due to SARS-CoV-2. There were no maternal deaths. The following gestational complications were observed: one stillbirth, one preterm labor, one preterm prelabor rupture of membranes, and one fetal growth restriction. Four deliveries were eutocic, two vacuum-assisted deliveries and five were cesarean sections. The indications for cesarean section were obstetric. Conclusions: SARS-CoV-2 infection was found in a minority of hospitalized pregnant women in this sample. Most are asymptomatic or have mild illness, from gestational complications to highlight stillbirth and preterm birth. There were no cases of vertical transmission by coronavirus. MDPI 2021-03-05 /pmc/articles/PMC7999825/ /pubmed/33807607 http://dx.doi.org/10.3390/medicina57030241 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ).
spellingShingle Article
de Vasconcelos Gaspar, Andreia
Santos Silva, Isabel
SARS-CoV-2 in Pregnancy—The First Wave
title SARS-CoV-2 in Pregnancy—The First Wave
title_full SARS-CoV-2 in Pregnancy—The First Wave
title_fullStr SARS-CoV-2 in Pregnancy—The First Wave
title_full_unstemmed SARS-CoV-2 in Pregnancy—The First Wave
title_short SARS-CoV-2 in Pregnancy—The First Wave
title_sort sars-cov-2 in pregnancy—the first wave
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7999825/
https://www.ncbi.nlm.nih.gov/pubmed/33807607
http://dx.doi.org/10.3390/medicina57030241
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