The Pathogenic Role of Interferons in the Hyperinflammatory Response on Adult-Onset Still’s Disease and Macrophage Activation Syndrome: Paving the Way towards New Therapeutic Targets

Adult-onset Still’s disease (AOSD) is a systemic inflammatory disorder of unknown aetiology affecting young adults, which is burdened by life-threatening complications, mostly macrophage activation syndrome (MAS). Interferons (IFNs) are signalling molecules that mediate a variety of biological funct...

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Detalles Bibliográficos
Autores principales: Di Cola, Ilenia, Ruscitti, Piero, Giacomelli, Roberto, Cipriani, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7999936/
https://www.ncbi.nlm.nih.gov/pubmed/33802085
http://dx.doi.org/10.3390/jcm10061164

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