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Antimicrobial Efficacy of Silver Nanoparticles as Root Canal Irrigant’s: A Systematic Review

Removal of microbes is imperative during endodontic therapy. Due to their antimicrobial property, silver nanoparticles have been used for endodontic irrigation of the root canals. The objective of the present study was to provide a qualitative analysis of the published literature assessing silver na...

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Autores principales: Bhandi, Shilpa, Mehta, Deepak, Mashyakhy, Mohammed, Chohan, Hitesh, Testarelli, Luca, Thomas, Jacob, Dhillon, Harnoor, Raj, A. Thirumal, Madapusi Balaji, Thodur, Varadarajan, Saranya, Patil, Shankargouda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7999954/
https://www.ncbi.nlm.nih.gov/pubmed/33801820
http://dx.doi.org/10.3390/jcm10061152
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author Bhandi, Shilpa
Mehta, Deepak
Mashyakhy, Mohammed
Chohan, Hitesh
Testarelli, Luca
Thomas, Jacob
Dhillon, Harnoor
Raj, A. Thirumal
Madapusi Balaji, Thodur
Varadarajan, Saranya
Patil, Shankargouda
author_facet Bhandi, Shilpa
Mehta, Deepak
Mashyakhy, Mohammed
Chohan, Hitesh
Testarelli, Luca
Thomas, Jacob
Dhillon, Harnoor
Raj, A. Thirumal
Madapusi Balaji, Thodur
Varadarajan, Saranya
Patil, Shankargouda
author_sort Bhandi, Shilpa
collection PubMed
description Removal of microbes is imperative during endodontic therapy. Due to their antimicrobial property, silver nanoparticles have been used for endodontic irrigation of the root canals. The objective of the present study was to provide a qualitative analysis of the published literature assessing silver nanoparticles as root canal irrigants. A search of PubMed, SCOPUS, Web of Science, and Embase databases was done without any time restriction. Articles published in English were included. Data were extracted and the risk of bias was assessed. Of the 154 studies identified, after screening according to the inclusion criteria, five in vitro studies were included. The results indicate that silver nanoparticles have an anti-microbial effect to varying degrees depending on certain factors. Within the limitations of the present studies that have a moderate to low risk of bias, an antimicrobial effect of silver nanoparticles is observed. Silver nanoparticles have the potential to be used as endodontic irrigants, although their efficacy depends on particle size and the duration of contact which require further investigation.
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spelling pubmed-79999542021-03-28 Antimicrobial Efficacy of Silver Nanoparticles as Root Canal Irrigant’s: A Systematic Review Bhandi, Shilpa Mehta, Deepak Mashyakhy, Mohammed Chohan, Hitesh Testarelli, Luca Thomas, Jacob Dhillon, Harnoor Raj, A. Thirumal Madapusi Balaji, Thodur Varadarajan, Saranya Patil, Shankargouda J Clin Med Review Removal of microbes is imperative during endodontic therapy. Due to their antimicrobial property, silver nanoparticles have been used for endodontic irrigation of the root canals. The objective of the present study was to provide a qualitative analysis of the published literature assessing silver nanoparticles as root canal irrigants. A search of PubMed, SCOPUS, Web of Science, and Embase databases was done without any time restriction. Articles published in English were included. Data were extracted and the risk of bias was assessed. Of the 154 studies identified, after screening according to the inclusion criteria, five in vitro studies were included. The results indicate that silver nanoparticles have an anti-microbial effect to varying degrees depending on certain factors. Within the limitations of the present studies that have a moderate to low risk of bias, an antimicrobial effect of silver nanoparticles is observed. Silver nanoparticles have the potential to be used as endodontic irrigants, although their efficacy depends on particle size and the duration of contact which require further investigation. MDPI 2021-03-10 /pmc/articles/PMC7999954/ /pubmed/33801820 http://dx.doi.org/10.3390/jcm10061152 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Bhandi, Shilpa
Mehta, Deepak
Mashyakhy, Mohammed
Chohan, Hitesh
Testarelli, Luca
Thomas, Jacob
Dhillon, Harnoor
Raj, A. Thirumal
Madapusi Balaji, Thodur
Varadarajan, Saranya
Patil, Shankargouda
Antimicrobial Efficacy of Silver Nanoparticles as Root Canal Irrigant’s: A Systematic Review
title Antimicrobial Efficacy of Silver Nanoparticles as Root Canal Irrigant’s: A Systematic Review
title_full Antimicrobial Efficacy of Silver Nanoparticles as Root Canal Irrigant’s: A Systematic Review
title_fullStr Antimicrobial Efficacy of Silver Nanoparticles as Root Canal Irrigant’s: A Systematic Review
title_full_unstemmed Antimicrobial Efficacy of Silver Nanoparticles as Root Canal Irrigant’s: A Systematic Review
title_short Antimicrobial Efficacy of Silver Nanoparticles as Root Canal Irrigant’s: A Systematic Review
title_sort antimicrobial efficacy of silver nanoparticles as root canal irrigant’s: a systematic review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7999954/
https://www.ncbi.nlm.nih.gov/pubmed/33801820
http://dx.doi.org/10.3390/jcm10061152
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