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Garcinol Attenuates Lipoprotein(a)-Induced Oxidative Stress and Inflammatory Cytokine Production in Ventricular Cardiomyocyte through α7-Nicotinic Acetylcholine Receptor-Mediated Inhibition of the p38 MAPK and NF-κB Signaling Pathways
Garcinol, a nicotinic acetylcholine receptor (nAChR) antagonist, has recently been established as an anti-inflammation agent. However, the molecular mechanism by which garcinol suppresses inflammation in the context of acute myocardial infarction (AMI) remains unclear. Hypothesis: We hypothesized th...
Autores principales: | Chang, Nen-Chung, Yeh, Chi-Tai, Lin, Yen-Kuang, Kuo, Kuang-Tai, Fong, Iat-Hang, Kounis, Nicholas G., Hu, Patrick, Hung, Ming-Yow |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000018/ https://www.ncbi.nlm.nih.gov/pubmed/33809417 http://dx.doi.org/10.3390/antiox10030461 |
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