Toxin-Activating Stapled Peptides Discovered by Structural Analysis Were Identified as New Therapeutic Candidates That Trigger Antibacterial Activity against Mycobacterium tuberculosis in the Mycobacterium smegmatis Model

The structure-function relationships of toxin-antitoxin (TA) systems from Mycobacterium tuberculosis have prompted the development of novel and effective antimicrobial agents that selectively target this organism. The artificial activation of toxins by peptide inhibitors can lead to the growth arres...

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Detalles Bibliográficos
Autores principales: Kang, Sung-Min, Moon, Heejo, Han, Sang-Woo, Kim, Byeong Wook, Kim, Do-Hee, Kim, Byeong Moon, Lee, Bong-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000039/
https://www.ncbi.nlm.nih.gov/pubmed/33801872
http://dx.doi.org/10.3390/microorganisms9030568

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