Protective Effect of Nasal Colonisation with ∆cps/piaA and ∆cps/proABC Streptococcus pneumoniae Strains against Recolonisation and Invasive Infection

Rationale: Nasopharyngeal administration of live virulence-attenuated Streptococcus pneumoniae strains is a potential novel preventative strategy. One target for creating reduced virulence S. pneumoniae strains is the capsule, but loss of the capsule reduces the duration of S. pneumoniae colonisatio...

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Detalles Bibliográficos
Autores principales: Ramos-Sevillano, Elisa, Ercoli, Giuseppe, Guerra-Assunção, José Afonso, Felgner, Philip, Ramiro de Assis, Rafael, Nakajima, Rie, Goldblatt, David, Tetteh, Kevin Kweku Adjei, Heyderman, Robert Simon, Gordon, Stephen Brian, Ferreria, Daniela Mulari, Brown, Jeremy Stuart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000150/
https://www.ncbi.nlm.nih.gov/pubmed/33804077
http://dx.doi.org/10.3390/vaccines9030261

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