Cargando…

Molecular Mechanism of Vitamin K2 Protection against Amyloid-β-Induced Cytotoxicity

The pathological role of vitamin K2 in Alzheimer’s disease (AD) involves a definite link between impaired cognitive functions and decreased serum vitamin K levels. Vitamin K2 supplementation may have a protective effect on AD. However, the mechanism underlying vitamin K2 protection has not been eluc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huang, Shu-Hsiang, Fang, Sheng-Ting, Chen, Yi-Cheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000266/ https://www.ncbi.nlm.nih.gov/pubmed/33805625 http://dx.doi.org/10.3390/biom11030423

Ejemplares similares

Mechanistic insights into the protective roles of polyphosphate against amyloid cytotoxicity
por: Lempart, Justine, et al.
Publicado: (2019)

The Potential Protective Effect of Curcumin on Amyloid-β-42 Induced Cytotoxicity in HT-22 Cells
por: Zhang, Lu, et al.
Publicado: (2018)

Brazilin inhibits amyloid β-protein fibrillogenesis, remodels amyloid fibrils and reduces amyloid cytotoxicity
por: Du, Wen-Jie, et al.
Publicado: (2015)

Adiponectin is Protective against Oxidative Stress Induced Cytotoxicity in Amyloid-Beta Neurotoxicity
por: Chan, Koon-Ho, et al.
Publicado: (2012)

TMPyP Inhibits Amyloid-β Aggregation and Alleviates Amyloid-Induced Cytotoxicity
por: Fan, Yujuan, et al.
Publicado: (2017)

Combinations of Vitamin A and Vitamin E Metabolites Confer Resilience against Amyloid-β Aggregation
por: Joshi, Priyanka, et al.
Publicado: (2023)

β-amyloid cytotoxicity is prevented by natural achillolide A
por: Elmann, Anat, et al.
Publicado: (2018)

Intracellular Cleavage of Amyloid β by a Viral Protease NIa Prevents Amyloid β-Mediated Cytotoxicity
por: Shin, Baehyun, et al.
Publicado: (2014)

Vitamin K(2) protects against Aβ42-induced neurotoxicity by activating autophagy and improving mitochondrial function in Drosophila
por: Lin, Xiaohui, et al.
Publicado: (2021)

Chitosan Oligosaccharides Attenuate Amyloid Formation of hIAPP and Protect Pancreatic β-Cells from Cytotoxicity
por: Meng, Qin-Yu, et al.
Publicado: (2020)

Protection against β-amyloid-induced synaptic and memory impairments via altering β-amyloid assembly by bis(heptyl)-cognitin
por: Chang, Lan, et al.
Publicado: (2015)

The Molecular Mechanisms of Oleanane Aldehyde-β-enone Cytotoxicity against Doxorubicin-Resistant Cancer Cells
por: Moiseeva, Natalia, et al.
Publicado: (2023)

Dual Specificity Phosphatase 6 Protects Neural Stem Cells from β-Amyloid-Induced Cytotoxicity through ERK1/2 Inactivation
por: Liao, Wang, et al.
Publicado: (2018)

Thiamine and benfotiamine protect neuroblastoma cells against paraquat and β-amyloid toxicity by a coenzyme-independent mechanism
por: Sambon, Margaux, et al.
Publicado: (2019)

Molecular mechanisms of amyloid disaggregation
por: Low, Kimberly Jia Yi, et al.
Publicado: (2021)

Elucidating the Inhibitory Potential of Designed Peptides Against Amyloid Fibrillation and Amyloid Associated Cytotoxicity
por: Siddiqi, Mohammad K., et al.
Publicado: (2018)

Common molecular mechanism of amyloid pore formation by Alzheimer’s β-amyloid peptide and α-synuclein
por: Di Scala, Coralie, et al.
Publicado: (2016)

Alzheimer’s amyloid-β A2T variant and its N-terminal peptides inhibit amyloid-β fibrillization and rescue the induced cytotoxicity
por: Lin, Tien-Wei, et al.
Publicado: (2017)

Structural polymorphism and cytotoxicity of brain‐derived β‐amyloid extracts
por: Al Adem, Kenana, et al.
Publicado: (2023)

Acteoside and Isoacteoside Protect Amyloid β Peptide Induced Cytotoxicity, Cognitive Deficit and Neurochemical Disturbances In Vitro and In Vivo
por: Shiao, Young-Ji, et al.
Publicado: (2017)

Inhibition of Amyloid β-Induced Lipid Membrane Permeation and Amyloid β Aggregation by K162
por: Mrdenovic, Dusan, et al.
Publicado: (2021)

Mechanisms of action of naturally occurring antibodies against β-amyloid on microglia
por: Gold, Maike, et al.
Publicado: (2013)

The α5β1 Integrin Mediates Elimination of Amyloid-β Peptide and Protects Against Apoptosis
por: Matter, Michelle L., et al.
Publicado: (1998)

Protective role of human insulin against the cytotoxicity associated with human mutant S20G islet amyloid polypeptide
por: Morita, Shuhei, et al.
Publicado: (2013)

Ginkgolides protect against amyloid-β(1–42)-mediated synapse damage in vitro
por: Bate, Clive, et al.
Publicado: (2008)

Progranulin Protects against Amyloid β Deposition and Toxicity in Alzheimer’s Disease Mouse Models
por: Minami, S. Sakura, et al.
Publicado: (2014)

Pharmacological sequestration of mitochondrial calcium uptake protects against dementia and β-amyloid neurotoxicity
por: Shevtsova, Elena F., et al.
Publicado: (2022)

Prostaglandin F2α protects against pericyte apoptosis by inhibiting the PI3K/Akt/GSK3β/β-catenin signaling pathway
por: Cheng, Ying, et al.
Publicado: (2021)

Prion-Like Behavior and Tau-dependent Cytotoxicity of Pyroglutamylated β-Amyloid
por: Nussbaum, Justin M., et al.
Publicado: (2012)

Amyloid-β with isomerized Asp7 cytotoxicity is coupled to protein phosphorylation
por: Zatsepina, O. G., et al.
Publicado: (2018)

UBB(+1) reduces amyloid-β cytotoxicity by activation of autophagy in yeast
por: Chen, Xin, et al.
Publicado: (2021)

Low and High Molecular Weight FGF-2 Have Differential Effects on Astrocyte Proliferation, but Are Both Protective Against Aβ-Induced Cytotoxicity
por: Chen, Xi, et al.
Publicado: (2020)

The Amyloid Forming Peptides Islet Amyloid Polypeptide and Amyloid β Interact at the Molecular Level
por: Wang, Ye, et al.
Publicado: (2021)

Linagliptin Protects Human SH-SY5Y Neuroblastoma Cells against Amyloid-β Cytotoxicity via the Activation of Wnt1 and Suppression of IL-6 Release
por: Sedighi, Mohsen, et al.
Publicado: (2021)

Thermal cycling protects SH-SY5Y cells against hydrogen peroxide and β-amyloid-induced cell injury through stress response mechanisms involving Akt pathway
por: Chen, Wei-Ting, et al.
Publicado: (2020)

Anticholinergic Drugs Interact With Neuroprotective Chaperone L-PGDS and Modulate Cytotoxicity of Aβ Amyloids
por: Low, Kimberly Jia Yi, et al.
Publicado: (2020)

Neuronal Cx3cr1 Deficiency Protects against Amyloid β-Induced Neurotoxicity
por: Dworzak, Jenny, et al.
Publicado: (2015)

NKX6.3 protects against gastric mucosal atrophy by downregulating β-amyloid production
por: Yoon, Jung Hwan, et al.
Publicado: (2019)

Cystatin C regulates the cytotoxicity of infection‐induced endothelial‐derived β‐amyloid
por: Balczon, Ron, et al.
Publicado: (2020)

Evidence for a Strong Relationship between the Cytotoxicity and Intracellular Location of β-Amyloid
por: Haque, Md. Aminul, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_219321n49cnae9d91f0ieftip6