Mutations of Intrinsically Disordered Protein Regions Can Drive Cancer but Lack Therapeutic Strategies

Many proteins contain intrinsically disordered regions (IDRs) which carry out important functions without relying on a single well-defined conformation. IDRs are increasingly recognized as critical elements of regulatory networks and have been also associated with cancer. However, it is unknown whet...

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Detalles Bibliográficos
Autores principales: Mészáros, Bálint, Hajdu-Soltész, Borbála, Zeke, András, Dosztányi, Zsuzsanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000335/
https://www.ncbi.nlm.nih.gov/pubmed/33806614
http://dx.doi.org/10.3390/biom11030381

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000335/
https://www.ncbi.nlm.nih.gov/pubmed/33806614
http://dx.doi.org/10.3390/biom11030381

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