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Mutations of Intrinsically Disordered Protein Regions Can Drive Cancer but Lack Therapeutic Strategies
Many proteins contain intrinsically disordered regions (IDRs) which carry out important functions without relying on a single well-defined conformation. IDRs are increasingly recognized as critical elements of regulatory networks and have been also associated with cancer. However, it is unknown whet...
Autores principales: | Mészáros, Bálint, Hajdu-Soltész, Borbála, Zeke, András, Dosztányi, Zsuzsanna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000335/ https://www.ncbi.nlm.nih.gov/pubmed/33806614 http://dx.doi.org/10.3390/biom11030381 |
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