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Effective Small Molecule Antibacterials from a Novel Anti-Protein Secretion Screen
The increasing problem of bacterial resistance to antibiotics underscores the urgent need for new antibacterials. Protein export pathways are attractive potential targets. The Sec pathway is essential for bacterial viability and includes components that are absent from eukaryotes. Here, we used a ne...
Autores principales: | Hamed, Mohamed Belal, Burchacka, Ewa, Angus, Liselotte, Marchand, Arnaud, De Geyter, Jozefien, Loos, Maria S., Anné, Jozef, Klaassen, Hugo, Chaltin, Patrick, Karamanou, Spyridoula, Economou, Anastassios |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000395/ https://www.ncbi.nlm.nih.gov/pubmed/33805695 http://dx.doi.org/10.3390/microorganisms9030592 |
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