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Elution Kinetics from Antibiotic-Loaded Calcium Sulfate Beads, Antibiotic-Loaded Polymethacrylate Spacers, and a Powdered Antibiotic Bolus for Surgical Site Infections in a Novel In Vitro Draining Knee Model
Antibiotic-tolerant bacterial biofilms are notorious in causing PJI. Antibiotic loaded calcium sulfate bead (CSB) bone void fillers and PMMA cement and powdered vancomycin (VP) have been used to achieve high local antibiotic concentrations; however, the effect of drainage on concentration is poorly...
Autores principales: | Moore, Kelly, Os, Rebecca Wilson-van, Dusane, Devendra H., Brooks, Jacob R., Delury, Craig, Aiken, Sean S., Laycock, Phillip A., Sullivan, Anne C., Granger, Jeffrey F., Dipane, Matthew V., McPherson, Edward J., Stoodley, Paul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000420/ https://www.ncbi.nlm.nih.gov/pubmed/33800299 http://dx.doi.org/10.3390/antibiotics10030270 |
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