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Structural and Functional Characterization of the ABCC6 Transporter in Hepatic Cells: Role on PXE, Cancer Therapy and Drug Resistance

Pseudoxanthoma elasticum (PXE) is a complex autosomal recessive disease caused by mutations of ABCC6 transporter and characterized by ectopic mineralization of soft connective tissues. Compared to the other ABC transporters, very few studies are available to explain the structural components and wor...

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Detalles Bibliográficos
Autores principales:	Bisaccia, Faustino, Koshal, Prashant, Abruzzese, Vittorio, Castiglione Morelli, Maria Antonietta, Ostuni, Angela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000515/ https://www.ncbi.nlm.nih.gov/pubmed/33799762 http://dx.doi.org/10.3390/ijms22062858

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