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Design and Fabrication of a New Wearable Pressure Sensor for Blood Pressure Monitoring

In recent years, research into the field of materials for flexible sensors and fabrication techniques directed towards wearable devices has helped to raise awareness of the need for new sensors with healthcare applicability. Our goal was to create a wearable flexible pressure sensor that could be in...

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Autores principales: Ion, Marian, Dinulescu, Silviu, Firtat, Bogdan, Savin, Mihaela, Ionescu, Octavian N., Moldovan, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000553/
https://www.ncbi.nlm.nih.gov/pubmed/33809497
http://dx.doi.org/10.3390/s21062075
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author Ion, Marian
Dinulescu, Silviu
Firtat, Bogdan
Savin, Mihaela
Ionescu, Octavian N.
Moldovan, Carmen
author_facet Ion, Marian
Dinulescu, Silviu
Firtat, Bogdan
Savin, Mihaela
Ionescu, Octavian N.
Moldovan, Carmen
author_sort Ion, Marian
collection PubMed
description In recent years, research into the field of materials for flexible sensors and fabrication techniques directed towards wearable devices has helped to raise awareness of the need for new sensors with healthcare applicability. Our goal was to create a wearable flexible pressure sensor that could be integrated into a clinically approved blood pressure monitoring device. The sensor is built from a microfluidic channel encapsulated between two polymer layers, one layer being covered by metal transducers and the other being a flexible membrane containing the microfluidic channel, which also acts as a sealant for the structure. The applied external pressure deforms the channel, causing changes in resistance to the microfluidic layer. Electrical characterization has been performed in 5 different configurations, using alternating current (AC) and (DC) direct current measurements. The AC measurements for the fabricated pressure sensor resulted in impedance values at tens of hundreds of kOhm. Our sensor proved to have a high sensitivity for pressure values between 0 and 150 mm Hg, being subjected to repeatable external forces. The novelty presented in our work consists in the unique technological flow for the fabrication of the flexible wearable pressure sensor. The proposed miniaturized pressure sensor will ensure flexibility, low production cost and ease of use. It is made of very sensitive microfluidic elements and biocompatible materials and can be integrated into a wearable cuffless device for continuous blood pressure monitoring.
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spelling pubmed-80005532021-03-28 Design and Fabrication of a New Wearable Pressure Sensor for Blood Pressure Monitoring Ion, Marian Dinulescu, Silviu Firtat, Bogdan Savin, Mihaela Ionescu, Octavian N. Moldovan, Carmen Sensors (Basel) Article In recent years, research into the field of materials for flexible sensors and fabrication techniques directed towards wearable devices has helped to raise awareness of the need for new sensors with healthcare applicability. Our goal was to create a wearable flexible pressure sensor that could be integrated into a clinically approved blood pressure monitoring device. The sensor is built from a microfluidic channel encapsulated between two polymer layers, one layer being covered by metal transducers and the other being a flexible membrane containing the microfluidic channel, which also acts as a sealant for the structure. The applied external pressure deforms the channel, causing changes in resistance to the microfluidic layer. Electrical characterization has been performed in 5 different configurations, using alternating current (AC) and (DC) direct current measurements. The AC measurements for the fabricated pressure sensor resulted in impedance values at tens of hundreds of kOhm. Our sensor proved to have a high sensitivity for pressure values between 0 and 150 mm Hg, being subjected to repeatable external forces. The novelty presented in our work consists in the unique technological flow for the fabrication of the flexible wearable pressure sensor. The proposed miniaturized pressure sensor will ensure flexibility, low production cost and ease of use. It is made of very sensitive microfluidic elements and biocompatible materials and can be integrated into a wearable cuffless device for continuous blood pressure monitoring. MDPI 2021-03-16 /pmc/articles/PMC8000553/ /pubmed/33809497 http://dx.doi.org/10.3390/s21062075 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Ion, Marian
Dinulescu, Silviu
Firtat, Bogdan
Savin, Mihaela
Ionescu, Octavian N.
Moldovan, Carmen
Design and Fabrication of a New Wearable Pressure Sensor for Blood Pressure Monitoring
title Design and Fabrication of a New Wearable Pressure Sensor for Blood Pressure Monitoring
title_full Design and Fabrication of a New Wearable Pressure Sensor for Blood Pressure Monitoring
title_fullStr Design and Fabrication of a New Wearable Pressure Sensor for Blood Pressure Monitoring
title_full_unstemmed Design and Fabrication of a New Wearable Pressure Sensor for Blood Pressure Monitoring
title_short Design and Fabrication of a New Wearable Pressure Sensor for Blood Pressure Monitoring
title_sort design and fabrication of a new wearable pressure sensor for blood pressure monitoring
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000553/
https://www.ncbi.nlm.nih.gov/pubmed/33809497
http://dx.doi.org/10.3390/s21062075
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