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Oligodendrocyte Dysfunction in Amyotrophic Lateral Sclerosis: Mechanisms and Therapeutic Perspectives

Myelin is the lipid-rich structure formed by oligodendrocytes (OLs) that wraps the axons in multilayered sheaths, assuring protection, efficient saltatory signal conduction and metabolic support to neurons. In the last few years, the impact of OL dysfunction and myelin damage has progressively recei...

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Detalles Bibliográficos
Autores principales: Raffaele, Stefano, Boccazzi, Marta, Fumagalli, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000560/
https://www.ncbi.nlm.nih.gov/pubmed/33807572
http://dx.doi.org/10.3390/cells10030565