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Factors affecting adherence to treatment in children living with HIV

BACKGROUND: With the successful introduction of ART, the life expectancy of children living with HIV (CLHIV) is substantially increased. However, strict compliance is a necessary step to begin with as noncompliance is again associated with its own demerits of incomplete suppression and decreasing th...

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Autores principales: Verma, Deepshikha, Bachani, Damodar, Acharya, Anita Shankar, Seth, Anju, Hemal, Alok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000669/
https://www.ncbi.nlm.nih.gov/pubmed/33817591
http://dx.doi.org/10.4103/ijstd.IJSTD_43_18
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author Verma, Deepshikha
Bachani, Damodar
Acharya, Anita Shankar
Seth, Anju
Hemal, Alok
author_facet Verma, Deepshikha
Bachani, Damodar
Acharya, Anita Shankar
Seth, Anju
Hemal, Alok
author_sort Verma, Deepshikha
collection PubMed
description BACKGROUND: With the successful introduction of ART, the life expectancy of children living with HIV (CLHIV) is substantially increased. However, strict compliance is a necessary step to begin with as noncompliance is again associated with its own demerits of incomplete suppression and decreasing the overall survival of the patients. AIMS: The aim of this study was to measure factors associated with adherence to ART among CLHIV. MATERIALS AND METHODS: This is a 1-year follow-up study conducted from November 2012 to December 2013. A total of 171 children between 18 months and 15 years living with HIV and on ART attending the two ART centers of Delhi were enrolled in the study. Adherence and factors affecting adherence were obtained from the study participants using a semi-structured interview schedule. STATISTICAL ANALYSIS USED: Collected data were transformed into variables and analyzed into SPSS. All observations were in terms of mean, median, standard deviations, percentages, and proportions. Tests of significance such as Chi-square test and t-test were applied wherever required. RESULTS: In nearly 89% of the study participants, adherence to ART was ≥95% at the end of the study. The most common reason for nonadherence was forgetfulness (59%), and 57% of the parents/caretakers were facing monetary problems. Long distance, greater duration to reach center, and unavailability of the parents/caretakers were also quoted as problems. CONCLUSION: Adherence is genesis to successful treatment outcome and is strongly associated with availability of support by their parents/caretakers. Professional help along with guidance and encouragement is required not only at the caretaker level but also to the family as a whole.
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spelling pubmed-80006692021-04-01 Factors affecting adherence to treatment in children living with HIV Verma, Deepshikha Bachani, Damodar Acharya, Anita Shankar Seth, Anju Hemal, Alok Indian J Sex Transm Dis AIDS Original Article BACKGROUND: With the successful introduction of ART, the life expectancy of children living with HIV (CLHIV) is substantially increased. However, strict compliance is a necessary step to begin with as noncompliance is again associated with its own demerits of incomplete suppression and decreasing the overall survival of the patients. AIMS: The aim of this study was to measure factors associated with adherence to ART among CLHIV. MATERIALS AND METHODS: This is a 1-year follow-up study conducted from November 2012 to December 2013. A total of 171 children between 18 months and 15 years living with HIV and on ART attending the two ART centers of Delhi were enrolled in the study. Adherence and factors affecting adherence were obtained from the study participants using a semi-structured interview schedule. STATISTICAL ANALYSIS USED: Collected data were transformed into variables and analyzed into SPSS. All observations were in terms of mean, median, standard deviations, percentages, and proportions. Tests of significance such as Chi-square test and t-test were applied wherever required. RESULTS: In nearly 89% of the study participants, adherence to ART was ≥95% at the end of the study. The most common reason for nonadherence was forgetfulness (59%), and 57% of the parents/caretakers were facing monetary problems. Long distance, greater duration to reach center, and unavailability of the parents/caretakers were also quoted as problems. CONCLUSION: Adherence is genesis to successful treatment outcome and is strongly associated with availability of support by their parents/caretakers. Professional help along with guidance and encouragement is required not only at the caretaker level but also to the family as a whole. Wolters Kluwer - Medknow 2020 2020-07-31 /pmc/articles/PMC8000669/ /pubmed/33817591 http://dx.doi.org/10.4103/ijstd.IJSTD_43_18 Text en Copyright: © 2020 Indian Journal of Sexually Transmitted Diseases and AIDS http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Verma, Deepshikha
Bachani, Damodar
Acharya, Anita Shankar
Seth, Anju
Hemal, Alok
Factors affecting adherence to treatment in children living with HIV
title Factors affecting adherence to treatment in children living with HIV
title_full Factors affecting adherence to treatment in children living with HIV
title_fullStr Factors affecting adherence to treatment in children living with HIV
title_full_unstemmed Factors affecting adherence to treatment in children living with HIV
title_short Factors affecting adherence to treatment in children living with HIV
title_sort factors affecting adherence to treatment in children living with hiv
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000669/
https://www.ncbi.nlm.nih.gov/pubmed/33817591
http://dx.doi.org/10.4103/ijstd.IJSTD_43_18
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