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Study of Two Constraints Impacting Measurements of Human Glycemia Using a Microwave Sensor

The measurement of glycemia is impacted by several constraints; those constraints have to be identified and quantified when designing an electromagnetic noninvasive sensor. The second phase concerns the level of the influence of these constraints. In this work, we investigated the impact of vein rad...

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Detalles Bibliográficos
Autores principales: Zidane, Mohamed Amine, Amar, Hichem, Rouane, Amar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000743/
https://www.ncbi.nlm.nih.gov/pubmed/33804224
http://dx.doi.org/10.3390/bios11030083
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author Zidane, Mohamed Amine
Amar, Hichem
Rouane, Amar
author_facet Zidane, Mohamed Amine
Amar, Hichem
Rouane, Amar
author_sort Zidane, Mohamed Amine
collection PubMed
description The measurement of glycemia is impacted by several constraints; those constraints have to be identified and quantified when designing an electromagnetic noninvasive sensor. The second phase concerns the level of the influence of these constraints. In this work, we investigated the impact of vein radius located in the forearm on a resonant microwave sensor to measure glycemia. We performed a numerical simulation using COMSOL Multiphysics of a proposed tissue model that was in contact with a microwave resonator. Some other factors affect the measurement, such as temperature, perfusion, sensor positioning and motion, tissue heterogeneity, and other biological activity. The sensor must be robust to the above-mentioned constraints. Because vein size changes from one person to another, the dielectric properties seen by the sensor will be different. This has been demonstrated by the change created in the resonance frequency of the simulated sensor for different vein sizes. The second constraint that was assessed is the dosimetry. The specific absorption rate (SAR) of any electromagnetic device should be evaluated and compared with SAR limits in the safety standards to ensure the safety of the user. Simulation results are in good agreement with SAR limits in the safety standards.
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spelling pubmed-80007432021-03-28 Study of Two Constraints Impacting Measurements of Human Glycemia Using a Microwave Sensor Zidane, Mohamed Amine Amar, Hichem Rouane, Amar Biosensors (Basel) Article The measurement of glycemia is impacted by several constraints; those constraints have to be identified and quantified when designing an electromagnetic noninvasive sensor. The second phase concerns the level of the influence of these constraints. In this work, we investigated the impact of vein radius located in the forearm on a resonant microwave sensor to measure glycemia. We performed a numerical simulation using COMSOL Multiphysics of a proposed tissue model that was in contact with a microwave resonator. Some other factors affect the measurement, such as temperature, perfusion, sensor positioning and motion, tissue heterogeneity, and other biological activity. The sensor must be robust to the above-mentioned constraints. Because vein size changes from one person to another, the dielectric properties seen by the sensor will be different. This has been demonstrated by the change created in the resonance frequency of the simulated sensor for different vein sizes. The second constraint that was assessed is the dosimetry. The specific absorption rate (SAR) of any electromagnetic device should be evaluated and compared with SAR limits in the safety standards to ensure the safety of the user. Simulation results are in good agreement with SAR limits in the safety standards. MDPI 2021-03-15 /pmc/articles/PMC8000743/ /pubmed/33804224 http://dx.doi.org/10.3390/bios11030083 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ).
spellingShingle Article
Zidane, Mohamed Amine
Amar, Hichem
Rouane, Amar
Study of Two Constraints Impacting Measurements of Human Glycemia Using a Microwave Sensor
title Study of Two Constraints Impacting Measurements of Human Glycemia Using a Microwave Sensor
title_full Study of Two Constraints Impacting Measurements of Human Glycemia Using a Microwave Sensor
title_fullStr Study of Two Constraints Impacting Measurements of Human Glycemia Using a Microwave Sensor
title_full_unstemmed Study of Two Constraints Impacting Measurements of Human Glycemia Using a Microwave Sensor
title_short Study of Two Constraints Impacting Measurements of Human Glycemia Using a Microwave Sensor
title_sort study of two constraints impacting measurements of human glycemia using a microwave sensor
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000743/
https://www.ncbi.nlm.nih.gov/pubmed/33804224
http://dx.doi.org/10.3390/bios11030083
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