Structure-Based Virtual Screening: Identification of a Novel NS2B-NS3 Protease Inhibitor with Potent Antiviral Activity against Zika and Dengue Viruses

Zika virus (ZIKV), which is associated with severe diseases in humans, has spread rapidly and globally since its emergence. ZIKV and dengue virus (DENV) are closely related, and antibody-dependent enhancement (ADE) of infection between cocirculating ZIKV and DENV may exacerbate disease. Despite thes...

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Detalles Bibliográficos
Autores principales: Shin, Hye Jin, Kim, Mi-Hwa, Lee, Joo-Youn, Hwang, Insu, Yoon, Gun Young, Kim, Hae Soo, Kwon, Young-Chan, Ahn, Dae-Gyun, Kim, Kyun-Do, Kim, Bum-Tae, Kim, Seong-Jun, Kim, Chonsaeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000814/
https://www.ncbi.nlm.nih.gov/pubmed/33800763
http://dx.doi.org/10.3390/microorganisms9030545

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000814/
https://www.ncbi.nlm.nih.gov/pubmed/33800763
http://dx.doi.org/10.3390/microorganisms9030545

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