Novel IMB16-4 Compound Loaded into Silica Nanoparticles Exhibits Enhanced Oral Bioavailability and Increased Anti-Liver Fibrosis In Vitro

Background: Liver fibrosis, as a common and refractory disease, is challenging to treat due to the lack of effective agents worldwide. Recently, we have developed a novel compound, N-(3,4,5-trichlorophenyl)-2(3-nitrobenzenesulfonamide) benzamide (IMB16-4), which is expected to have good potential ef...

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Detalles Bibliográficos
Autores principales: Niu, Xia, Wang, Xiaomei, Niu, Bingyu, Li, Guoqing, Yang, Xinyi, Wang, Yucheng, Li, Guiling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000840/
https://www.ncbi.nlm.nih.gov/pubmed/33799909
http://dx.doi.org/10.3390/molecules26061545

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000840/
https://www.ncbi.nlm.nih.gov/pubmed/33799909
http://dx.doi.org/10.3390/molecules26061545

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