Exploiting the Potential of Drosophila Models in Lysosomal Storage Disorders: Pathological Mechanisms and Drug Discovery

Lysosomal storage disorders (LSDs) represent a complex and heterogeneous group of rare genetic diseases due to mutations in genes coding for lysosomal enzymes, membrane proteins or transporters. This leads to the accumulation of undegraded materials within lysosomes and a broad range of severe clini...

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Detalles Bibliográficos
Autores principales: Rigon, Laura, De Filippis, Concetta, Napoli, Barbara, Tomanin, Rosella, Orso, Genny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000850/
https://www.ncbi.nlm.nih.gov/pubmed/33800050
http://dx.doi.org/10.3390/biomedicines9030268

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