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Transport of Non-Spherical Particles in Square Microchannel Flows: A Review

Understanding the behavior of a single particle flowing in a microchannel is a necessary step in designing and optimizing efficient microfluidic devices for the separation, concentration, counting, detecting, sorting, or mixing of particles in suspension. Although the inertial migration of spherical...

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Detalles Bibliográficos
Autores principales: Tohme, Tohme, Magaud, Pascale, Baldas, Lucien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000912/
https://www.ncbi.nlm.nih.gov/pubmed/33800014
http://dx.doi.org/10.3390/mi12030277
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author Tohme, Tohme
Magaud, Pascale
Baldas, Lucien
author_facet Tohme, Tohme
Magaud, Pascale
Baldas, Lucien
author_sort Tohme, Tohme
collection PubMed
description Understanding the behavior of a single particle flowing in a microchannel is a necessary step in designing and optimizing efficient microfluidic devices for the separation, concentration, counting, detecting, sorting, or mixing of particles in suspension. Although the inertial migration of spherical particles has been deeply investigated in the last two decades, most of the targeted applications involve shaped particles whose behavior in microflows is still far from being completely understood. While traveling in a channel, a particle both rotates and translates: it translates in the streamwise direction driven by the fluid flow but also in the cross-section perpendicular to the streamwise direction due to inertial effects. In addition, particles’ rotation and translation motions are coupled. Most of the existing works investigating the transport of particles in microchannels decouple their rotational and lateral migration behaviors: particle rotation is mainly studied in simple shear flows, whereas lateral migration is neglected, and studies on lateral migration mostly focus on spherical particles whose rotational behavior is simple. The aim of this review is to provide a summary of the different works existing in the literature on the inertial migration and the rotational behavior of non-spherical particles with a focus and discussion on the remaining scientific challenges in this field.
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spelling pubmed-80009122021-03-28 Transport of Non-Spherical Particles in Square Microchannel Flows: A Review Tohme, Tohme Magaud, Pascale Baldas, Lucien Micromachines (Basel) Review Understanding the behavior of a single particle flowing in a microchannel is a necessary step in designing and optimizing efficient microfluidic devices for the separation, concentration, counting, detecting, sorting, or mixing of particles in suspension. Although the inertial migration of spherical particles has been deeply investigated in the last two decades, most of the targeted applications involve shaped particles whose behavior in microflows is still far from being completely understood. While traveling in a channel, a particle both rotates and translates: it translates in the streamwise direction driven by the fluid flow but also in the cross-section perpendicular to the streamwise direction due to inertial effects. In addition, particles’ rotation and translation motions are coupled. Most of the existing works investigating the transport of particles in microchannels decouple their rotational and lateral migration behaviors: particle rotation is mainly studied in simple shear flows, whereas lateral migration is neglected, and studies on lateral migration mostly focus on spherical particles whose rotational behavior is simple. The aim of this review is to provide a summary of the different works existing in the literature on the inertial migration and the rotational behavior of non-spherical particles with a focus and discussion on the remaining scientific challenges in this field. MDPI 2021-03-07 /pmc/articles/PMC8000912/ /pubmed/33800014 http://dx.doi.org/10.3390/mi12030277 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ).
spellingShingle Review
Tohme, Tohme
Magaud, Pascale
Baldas, Lucien
Transport of Non-Spherical Particles in Square Microchannel Flows: A Review
title Transport of Non-Spherical Particles in Square Microchannel Flows: A Review
title_full Transport of Non-Spherical Particles in Square Microchannel Flows: A Review
title_fullStr Transport of Non-Spherical Particles in Square Microchannel Flows: A Review
title_full_unstemmed Transport of Non-Spherical Particles in Square Microchannel Flows: A Review
title_short Transport of Non-Spherical Particles in Square Microchannel Flows: A Review
title_sort transport of non-spherical particles in square microchannel flows: a review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000912/
https://www.ncbi.nlm.nih.gov/pubmed/33800014
http://dx.doi.org/10.3390/mi12030277
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