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Transport of Non-Spherical Particles in Square Microchannel Flows: A Review
Understanding the behavior of a single particle flowing in a microchannel is a necessary step in designing and optimizing efficient microfluidic devices for the separation, concentration, counting, detecting, sorting, or mixing of particles in suspension. Although the inertial migration of spherical...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000912/ https://www.ncbi.nlm.nih.gov/pubmed/33800014 http://dx.doi.org/10.3390/mi12030277 |
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author | Tohme, Tohme Magaud, Pascale Baldas, Lucien |
author_facet | Tohme, Tohme Magaud, Pascale Baldas, Lucien |
author_sort | Tohme, Tohme |
collection | PubMed |
description | Understanding the behavior of a single particle flowing in a microchannel is a necessary step in designing and optimizing efficient microfluidic devices for the separation, concentration, counting, detecting, sorting, or mixing of particles in suspension. Although the inertial migration of spherical particles has been deeply investigated in the last two decades, most of the targeted applications involve shaped particles whose behavior in microflows is still far from being completely understood. While traveling in a channel, a particle both rotates and translates: it translates in the streamwise direction driven by the fluid flow but also in the cross-section perpendicular to the streamwise direction due to inertial effects. In addition, particles’ rotation and translation motions are coupled. Most of the existing works investigating the transport of particles in microchannels decouple their rotational and lateral migration behaviors: particle rotation is mainly studied in simple shear flows, whereas lateral migration is neglected, and studies on lateral migration mostly focus on spherical particles whose rotational behavior is simple. The aim of this review is to provide a summary of the different works existing in the literature on the inertial migration and the rotational behavior of non-spherical particles with a focus and discussion on the remaining scientific challenges in this field. |
format | Online Article Text |
id | pubmed-8000912 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-80009122021-03-28 Transport of Non-Spherical Particles in Square Microchannel Flows: A Review Tohme, Tohme Magaud, Pascale Baldas, Lucien Micromachines (Basel) Review Understanding the behavior of a single particle flowing in a microchannel is a necessary step in designing and optimizing efficient microfluidic devices for the separation, concentration, counting, detecting, sorting, or mixing of particles in suspension. Although the inertial migration of spherical particles has been deeply investigated in the last two decades, most of the targeted applications involve shaped particles whose behavior in microflows is still far from being completely understood. While traveling in a channel, a particle both rotates and translates: it translates in the streamwise direction driven by the fluid flow but also in the cross-section perpendicular to the streamwise direction due to inertial effects. In addition, particles’ rotation and translation motions are coupled. Most of the existing works investigating the transport of particles in microchannels decouple their rotational and lateral migration behaviors: particle rotation is mainly studied in simple shear flows, whereas lateral migration is neglected, and studies on lateral migration mostly focus on spherical particles whose rotational behavior is simple. The aim of this review is to provide a summary of the different works existing in the literature on the inertial migration and the rotational behavior of non-spherical particles with a focus and discussion on the remaining scientific challenges in this field. MDPI 2021-03-07 /pmc/articles/PMC8000912/ /pubmed/33800014 http://dx.doi.org/10.3390/mi12030277 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ). |
spellingShingle | Review Tohme, Tohme Magaud, Pascale Baldas, Lucien Transport of Non-Spherical Particles in Square Microchannel Flows: A Review |
title | Transport of Non-Spherical Particles in Square Microchannel Flows: A Review |
title_full | Transport of Non-Spherical Particles in Square Microchannel Flows: A Review |
title_fullStr | Transport of Non-Spherical Particles in Square Microchannel Flows: A Review |
title_full_unstemmed | Transport of Non-Spherical Particles in Square Microchannel Flows: A Review |
title_short | Transport of Non-Spherical Particles in Square Microchannel Flows: A Review |
title_sort | transport of non-spherical particles in square microchannel flows: a review |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000912/ https://www.ncbi.nlm.nih.gov/pubmed/33800014 http://dx.doi.org/10.3390/mi12030277 |
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