Dietary Inclusion of Blood Plasma with Yeast (Saccharomyces cerevisiae) Supplementation Enhanced the Growth Performance, Nutrient Digestibility, Lactobacillus Count, and Reduced Gas Emissions in Weaning Pigs

SIMPLE SUMMARY: Since 20th century, the use of yeast (Saccharomyces cerevisiae) supplement has been increased in animals feed due to its promising effects and potential to brighten the livestock industry in future. The feed cost of blood plasma is very expensive and, due to its high cost, it has been used mainly in piglet diets. In this regard, we implemented 3% blood plasma with 3% yeast supplementation to piglets mainly from 0–7 days, and gradually reduced the concentration of blood plasma with yeast supplement to 1.5:1.5% from 8–21 days and observed how it affects the overall performance of pigs on the remaining days 22–42 fed only basal diet. As expected, piglets fed blood plasma with yeast supplement over 0–21 days has a great impact on the growth performance, nutrient digestibility, fecal microbial, and gas emission at the end of the experiment. Thus, we suggest that blood plasma with yeast could be an excellent alternative in the livestock industry. ABSTRACT: This experiment was performed to examine the hypothesis that blood plasma (BP) with yeast (Saccharomyces cerevisiae) supplement in the diet of weaning pigs could provoke the growth performance, nutrient digestibility, fecal microbial, and reduce harmful gas excretion. A total of one hundred and eighty healthy piglets were taken and assigned (complete random blocks) to three dietary treatments as: Phase 1: Treatment (TRT) 1-6% BP; TRT 2-3% BP + 3% yeast; TRT 3-6% yeast. Phase 2: TRT 1-3%; BP., TRT 2-1.5% BP + 1.5% yeast; TRT 3- 3% yeast. Phase 3: TRT 1- Control (CON) (Basal diet); TRT 2- CON; TRT 3- CON for six- weeks. Each treatment had twelve replicates and five (three gilts and two barrows) pigs per pen. Dietary inclusion of BP with yeast supplementation significantly increased the body weight of piglets during phase 2 (p = 0.003) and phase 3 (p = 0.032). In addition, TRT2 group piglets had a significant improvement in average daily gain at the end of each phase and overall (p = 0.047, 0.025, 0.018 and 0.012, respectively). At phase 3, TRT2 group piglets showed a significant improvement on nutrient digestibility of dry matter (p = 0.012) and nitrogen (p = 0.040). The fecal microbiota of TRT2 group piglets showed a tendency to increase the number of Lactobacillus counts at phase 1 (p = 0.07) and phase 2 (p = 0.06) as well as, a significant improvement at phase 3 (p = 0.021). In addition, TRT2 group piglets had trend to decrease NH(3) (p = 0.074) and H(2)S (p = 0.069) during phase 2, and significantly reduced NH(3) (p = 0.038) and H(2)S (p = 0.046) at phase 3. However, the fecal score of piglets remains unaffected during the entire trial. At the end of phase 1 piglets’ IgG (p = 0.008) was significantly increased with the inclusion of BP with yeast supplementation. Based on the positive effects on body weight, average daily gain, nutrient digestibility, Lactobacillus count, and reduced gas emission, we suggest that dietary supplement with BP and yeast in the diet of weaned piglet could serve as an excellent alternative to antibiotics growth promoters.