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Construction and Immunological Evaluation of an Adenoviral Vector-Based Vaccine Candidate for Lassa Fever

Lassa virus (LASV) is a rodent-borne arenavirus circulating in West African regions that causes Lassa fever (LF). LF is normally asymptomatic at the initial infection stage, but can progress to severe disease with multiorgan collapse and hemorrhagic fever. To date, the therapeutic choices are limite...

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Detalles Bibliográficos
Autores principales: Wang, Meirong, Li, Ruihua, Li, Yaohui, Yu, Changming, Chi, Xiangyang, Wu, Shipo, Liu, Shulin, Xu, Junjie, Chen, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001012/
https://www.ncbi.nlm.nih.gov/pubmed/33804206
http://dx.doi.org/10.3390/v13030484