Targeting the DEAD-Box RNA Helicase eIF4A with Rocaglates—A Pan-Antiviral Strategy for Minimizing the Impact of Future RNA Virus Pandemics

The increase in pandemics caused by RNA viruses of zoonotic origin highlights the urgent need for broad-spectrum antivirals against novel and re-emerging RNA viruses. Broad-spectrum antivirals could be deployed as first-line interventions during an outbreak while virus-specific drugs and vaccines ar...

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Detalles Bibliográficos
Autores principales: Taroncher-Oldenburg, Gaspar, Müller, Christin, Obermann, Wiebke, Ziebuhr, John, Hartmann, Roland K., Grünweller, Arnold
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001013/
https://www.ncbi.nlm.nih.gov/pubmed/33807988
http://dx.doi.org/10.3390/microorganisms9030540

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001013/
https://www.ncbi.nlm.nih.gov/pubmed/33807988
http://dx.doi.org/10.3390/microorganisms9030540

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