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Targeting the DEAD-Box RNA Helicase eIF4A with Rocaglates—A Pan-Antiviral Strategy for Minimizing the Impact of Future RNA Virus Pandemics

The increase in pandemics caused by RNA viruses of zoonotic origin highlights the urgent need for broad-spectrum antivirals against novel and re-emerging RNA viruses. Broad-spectrum antivirals could be deployed as first-line interventions during an outbreak while virus-specific drugs and vaccines ar...

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Detalles Bibliográficos
Autores principales:	Taroncher-Oldenburg, Gaspar, Müller, Christin, Obermann, Wiebke, Ziebuhr, John, Hartmann, Roland K., Grünweller, Arnold
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001013/ https://www.ncbi.nlm.nih.gov/pubmed/33807988 http://dx.doi.org/10.3390/microorganisms9030540

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