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Adipocyte-Mineralocorticoid Receptor Alters Mitochondrial Quality Control Leading to Mitochondrial Dysfunction and Senescence of Visceral Adipose Tissue
Mineralocorticoid receptor (MR) expression is increased in the adipose tissue (AT) of obese patients and animals. We previously demonstrated that adipocyte-MR overexpression in mice (Adipo-MROE mice) is associated with metabolic alterations. Moreover, we showed that MR regulates mitochondrial dysfun...
Autores principales: | Lefranc, Clara, Friederich-Persson, Malou, Foufelle, Fabienne, Nguyen Dinh Cat, Aurélie, Jaisser, Frédéric |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001019/ https://www.ncbi.nlm.nih.gov/pubmed/33809055 http://dx.doi.org/10.3390/ijms22062881 |
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