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Non-Metabolic Functions of PKM2 Contribute to Cervical Cancer Cell Proliferation Induced by the HPV16 E7 Oncoprotein

Pyruvate kinase M2 (PKM2) mainly catalyzes glycolysis, but it also exerts non-glycolytic functions in several cancers. While it has been shown to interact with the human papillomavirus 16 (HPV16) E7 oncoprotein, the functional significance of PKM2 in HPV-associated cervical cancer has been elusive....

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Detalles Bibliográficos
Autores principales: Lee, Seoung-Ae, Ho, Charles, Troxler, Madison, Lin, Chin-Yo, Chung, Sang-Hyuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001101/
https://www.ncbi.nlm.nih.gov/pubmed/33800513
http://dx.doi.org/10.3390/v13030433