Cargando…

Efficacy of Oral Sarolaner for the Treatment of Feline Otodectic Mange

Otodectes cynotis is a mite with a cosmopolitan distribution that is the primary agent for the development of otitis externa in feline species. The aim of this study was to evaluate the efficacy of the oral administration of sarolaner for the treatment of feline otodectic mange. We used 20 adult cat...

Descripción completa

Detalles Bibliográficos
Autores principales: Ribeiro Campos, Diefrey, de Oliveira Chaves, Jéssica Karoline, Gava Guimarães, Brena, Yin Nak, So, Pereira Salça de Almeida, Gabriela, Scalioni Gijsen, Isabela, de Moraes Intrieri, Juliana, Barbour Scott, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001191/
https://www.ncbi.nlm.nih.gov/pubmed/33804037
http://dx.doi.org/10.3390/pathogens10030341
Descripción
Sumario:Otodectes cynotis is a mite with a cosmopolitan distribution that is the primary agent for the development of otitis externa in feline species. The aim of this study was to evaluate the efficacy of the oral administration of sarolaner for the treatment of feline otodectic mange. We used 20 adult cats of both sexes that were naturally infested with O. cynotis. The mite infestation scoring was performed by video-otoscopy before treatment. The cats were randomized according to the infestation score and divided into two groups (treated and control). The treated group underwent oral administration of sarolaner in a single dose of 2–4 mg/kg. The evaluations were performed by video-otoscopy to evaluate the reduction of infestation score 2, 4, 6, 24 and 48 h and 7, 14, 21 and 28 days after medication. At the end of the study, the cats were sedated to enable the recovery of live and dead mites to determine efficacy. No adverse effects or laboratory changes were observed in these cats. Sarolaner showed 100% efficacy 48 h after treatment. Based on the results, a single oral dose of sarolaner was effective in controlling otodectic mange in naturally infested cats.