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The Janus Kinase Inhibitor Ruxolitinib Prevents Terminal Shock in a Mouse Model of Arenavirus Hemorrhagic Fever

Arenaviruses such as Lassa virus cause arenavirus hemorrhagic fever (AVHF), but protective vaccines and effective antiviral therapy remain unmet medical needs. Our prior work has revealed that inducible nitric oxide synthase (iNOS) induction by IFN-γ represents a key pathway to microvascular leak an...

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Detalles Bibliográficos
Autores principales:	Sahin, Mehmet, Remy, Melissa M., Merkler, Doron, Pinschewer, Daniel D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001354/ https://www.ncbi.nlm.nih.gov/pubmed/33803310 http://dx.doi.org/10.3390/microorganisms9030564

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