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Regulation of K(+) Conductance by a Hydrogen Bond in Kv2.1, Kv2.2, and Kv1.2 Channels
The slow inactivation of voltage-gated potassium (Kv) channels plays an important role in controlling cellular excitability. Recently, the two hydrogen bonds (H-bonds) formed by W434-D447 and T439-Y445 have been reported to control the slow inactivation in Shaker potassium channels. The four residue...
Autores principales: | Zhang, Yuchen, Zhang, Xuefeng, Liu, Cuiyun, Hu, Changlong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001480/ https://www.ncbi.nlm.nih.gov/pubmed/33803465 http://dx.doi.org/10.3390/membranes11030190 |
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