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iPSC-Cardiomyocyte Models of Brugada Syndrome—Achievements, Challenges and Future Perspectives
Brugada syndrome (BrS) is an inherited cardiac arrhythmia that predisposes to ventricular fibrillation and sudden cardiac death. It originates from oligogenic alterations that affect cardiac ion channels or their accessory proteins. The main hurdle for the study of the functional effects of those va...
Autores principales: | Nijak, Aleksandra, Saenen, Johan, Labro, Alain J., Schepers, Dorien, Loeys, Bart L., Alaerts, Maaike |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001521/ https://www.ncbi.nlm.nih.gov/pubmed/33802229 http://dx.doi.org/10.3390/ijms22062825 |
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