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Short-Pulse Lasers: A Versatile Tool in Creating Novel Nano-/Micro-Structures and Compositional Analysis for Healthcare and Wellbeing Challenges

Driven by flexibility, precision, repeatability and eco-friendliness, laser-based technologies have attracted great interest to engineer or to analyze materials in various fields including energy, environment, biology and medicine. A major advantage of laser processing relies on the ability to direc...

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Autores principales: Al-Kattan, Ahmed, Grojo, David, Drouet, Christophe, Mouskeftaras, Alexandros, Delaporte, Philippe, Casanova, Adrien, Robin, Jérôme D., Magdinier, Frédérique, Alloncle, Patricia, Constantinescu, Catalin, Motto-Ros, Vincent, Hermann, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001552/
https://www.ncbi.nlm.nih.gov/pubmed/33809072
http://dx.doi.org/10.3390/nano11030712
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author Al-Kattan, Ahmed
Grojo, David
Drouet, Christophe
Mouskeftaras, Alexandros
Delaporte, Philippe
Casanova, Adrien
Robin, Jérôme D.
Magdinier, Frédérique
Alloncle, Patricia
Constantinescu, Catalin
Motto-Ros, Vincent
Hermann, Jörg
author_facet Al-Kattan, Ahmed
Grojo, David
Drouet, Christophe
Mouskeftaras, Alexandros
Delaporte, Philippe
Casanova, Adrien
Robin, Jérôme D.
Magdinier, Frédérique
Alloncle, Patricia
Constantinescu, Catalin
Motto-Ros, Vincent
Hermann, Jörg
author_sort Al-Kattan, Ahmed
collection PubMed
description Driven by flexibility, precision, repeatability and eco-friendliness, laser-based technologies have attracted great interest to engineer or to analyze materials in various fields including energy, environment, biology and medicine. A major advantage of laser processing relies on the ability to directly structure matter at different scales and to prepare novel materials with unique physical and chemical properties. It is also a contact-free approach that makes it possible to work in inert or reactive liquid or gaseous environment. This leads today to a unique opportunity for designing, fabricating and even analyzing novel complex bio-systems. To illustrate this potential, in this paper, we gather our recent research on four types of laser-based methods relevant for nano-/micro-scale applications. First, we present and discuss pulsed laser ablation in liquid, exploited today for synthetizing ultraclean “bare” nanoparticles attractive for medicine and tissue engineering applications. Second, we discuss robust methods for rapid surface and bulk machining (subtractive manufacturing) at different scales by laser ablation. Among them, the microsphere-assisted laser surface engineering is detailed for its appropriateness to design structured substrates with hierarchically periodic patterns at nano-/micro-scale without chemical treatments. Third, we address the laser-induced forward transfer, a technology based on direct laser printing, to transfer and assemble a multitude of materials (additive structuring), including biological moiety without alteration of functionality. Finally, the fourth method is about chemical analysis: we present the potential of laser-induced breakdown spectroscopy, providing a unique tool for contact-free and space-resolved elemental analysis of organic materials. Overall, we present and discuss the prospect and complementarity of emerging reliable laser technologies, to address challenges in materials’ preparation relevant for the development of innovative multi-scale and multi-material platforms for bio-applications.
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spelling pubmed-80015522021-03-28 Short-Pulse Lasers: A Versatile Tool in Creating Novel Nano-/Micro-Structures and Compositional Analysis for Healthcare and Wellbeing Challenges Al-Kattan, Ahmed Grojo, David Drouet, Christophe Mouskeftaras, Alexandros Delaporte, Philippe Casanova, Adrien Robin, Jérôme D. Magdinier, Frédérique Alloncle, Patricia Constantinescu, Catalin Motto-Ros, Vincent Hermann, Jörg Nanomaterials (Basel) Review Driven by flexibility, precision, repeatability and eco-friendliness, laser-based technologies have attracted great interest to engineer or to analyze materials in various fields including energy, environment, biology and medicine. A major advantage of laser processing relies on the ability to directly structure matter at different scales and to prepare novel materials with unique physical and chemical properties. It is also a contact-free approach that makes it possible to work in inert or reactive liquid or gaseous environment. This leads today to a unique opportunity for designing, fabricating and even analyzing novel complex bio-systems. To illustrate this potential, in this paper, we gather our recent research on four types of laser-based methods relevant for nano-/micro-scale applications. First, we present and discuss pulsed laser ablation in liquid, exploited today for synthetizing ultraclean “bare” nanoparticles attractive for medicine and tissue engineering applications. Second, we discuss robust methods for rapid surface and bulk machining (subtractive manufacturing) at different scales by laser ablation. Among them, the microsphere-assisted laser surface engineering is detailed for its appropriateness to design structured substrates with hierarchically periodic patterns at nano-/micro-scale without chemical treatments. Third, we address the laser-induced forward transfer, a technology based on direct laser printing, to transfer and assemble a multitude of materials (additive structuring), including biological moiety without alteration of functionality. Finally, the fourth method is about chemical analysis: we present the potential of laser-induced breakdown spectroscopy, providing a unique tool for contact-free and space-resolved elemental analysis of organic materials. Overall, we present and discuss the prospect and complementarity of emerging reliable laser technologies, to address challenges in materials’ preparation relevant for the development of innovative multi-scale and multi-material platforms for bio-applications. MDPI 2021-03-12 /pmc/articles/PMC8001552/ /pubmed/33809072 http://dx.doi.org/10.3390/nano11030712 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ).
spellingShingle Review
Al-Kattan, Ahmed
Grojo, David
Drouet, Christophe
Mouskeftaras, Alexandros
Delaporte, Philippe
Casanova, Adrien
Robin, Jérôme D.
Magdinier, Frédérique
Alloncle, Patricia
Constantinescu, Catalin
Motto-Ros, Vincent
Hermann, Jörg
Short-Pulse Lasers: A Versatile Tool in Creating Novel Nano-/Micro-Structures and Compositional Analysis for Healthcare and Wellbeing Challenges
title Short-Pulse Lasers: A Versatile Tool in Creating Novel Nano-/Micro-Structures and Compositional Analysis for Healthcare and Wellbeing Challenges
title_full Short-Pulse Lasers: A Versatile Tool in Creating Novel Nano-/Micro-Structures and Compositional Analysis for Healthcare and Wellbeing Challenges
title_fullStr Short-Pulse Lasers: A Versatile Tool in Creating Novel Nano-/Micro-Structures and Compositional Analysis for Healthcare and Wellbeing Challenges
title_full_unstemmed Short-Pulse Lasers: A Versatile Tool in Creating Novel Nano-/Micro-Structures and Compositional Analysis for Healthcare and Wellbeing Challenges
title_short Short-Pulse Lasers: A Versatile Tool in Creating Novel Nano-/Micro-Structures and Compositional Analysis for Healthcare and Wellbeing Challenges
title_sort short-pulse lasers: a versatile tool in creating novel nano-/micro-structures and compositional analysis for healthcare and wellbeing challenges
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001552/
https://www.ncbi.nlm.nih.gov/pubmed/33809072
http://dx.doi.org/10.3390/nano11030712
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