Cargando…
Short-Pulse Lasers: A Versatile Tool in Creating Novel Nano-/Micro-Structures and Compositional Analysis for Healthcare and Wellbeing Challenges
Driven by flexibility, precision, repeatability and eco-friendliness, laser-based technologies have attracted great interest to engineer or to analyze materials in various fields including energy, environment, biology and medicine. A major advantage of laser processing relies on the ability to direc...
Autores principales: | , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001552/ https://www.ncbi.nlm.nih.gov/pubmed/33809072 http://dx.doi.org/10.3390/nano11030712 |
_version_ | 1783671256865832960 |
---|---|
author | Al-Kattan, Ahmed Grojo, David Drouet, Christophe Mouskeftaras, Alexandros Delaporte, Philippe Casanova, Adrien Robin, Jérôme D. Magdinier, Frédérique Alloncle, Patricia Constantinescu, Catalin Motto-Ros, Vincent Hermann, Jörg |
author_facet | Al-Kattan, Ahmed Grojo, David Drouet, Christophe Mouskeftaras, Alexandros Delaporte, Philippe Casanova, Adrien Robin, Jérôme D. Magdinier, Frédérique Alloncle, Patricia Constantinescu, Catalin Motto-Ros, Vincent Hermann, Jörg |
author_sort | Al-Kattan, Ahmed |
collection | PubMed |
description | Driven by flexibility, precision, repeatability and eco-friendliness, laser-based technologies have attracted great interest to engineer or to analyze materials in various fields including energy, environment, biology and medicine. A major advantage of laser processing relies on the ability to directly structure matter at different scales and to prepare novel materials with unique physical and chemical properties. It is also a contact-free approach that makes it possible to work in inert or reactive liquid or gaseous environment. This leads today to a unique opportunity for designing, fabricating and even analyzing novel complex bio-systems. To illustrate this potential, in this paper, we gather our recent research on four types of laser-based methods relevant for nano-/micro-scale applications. First, we present and discuss pulsed laser ablation in liquid, exploited today for synthetizing ultraclean “bare” nanoparticles attractive for medicine and tissue engineering applications. Second, we discuss robust methods for rapid surface and bulk machining (subtractive manufacturing) at different scales by laser ablation. Among them, the microsphere-assisted laser surface engineering is detailed for its appropriateness to design structured substrates with hierarchically periodic patterns at nano-/micro-scale without chemical treatments. Third, we address the laser-induced forward transfer, a technology based on direct laser printing, to transfer and assemble a multitude of materials (additive structuring), including biological moiety without alteration of functionality. Finally, the fourth method is about chemical analysis: we present the potential of laser-induced breakdown spectroscopy, providing a unique tool for contact-free and space-resolved elemental analysis of organic materials. Overall, we present and discuss the prospect and complementarity of emerging reliable laser technologies, to address challenges in materials’ preparation relevant for the development of innovative multi-scale and multi-material platforms for bio-applications. |
format | Online Article Text |
id | pubmed-8001552 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-80015522021-03-28 Short-Pulse Lasers: A Versatile Tool in Creating Novel Nano-/Micro-Structures and Compositional Analysis for Healthcare and Wellbeing Challenges Al-Kattan, Ahmed Grojo, David Drouet, Christophe Mouskeftaras, Alexandros Delaporte, Philippe Casanova, Adrien Robin, Jérôme D. Magdinier, Frédérique Alloncle, Patricia Constantinescu, Catalin Motto-Ros, Vincent Hermann, Jörg Nanomaterials (Basel) Review Driven by flexibility, precision, repeatability and eco-friendliness, laser-based technologies have attracted great interest to engineer or to analyze materials in various fields including energy, environment, biology and medicine. A major advantage of laser processing relies on the ability to directly structure matter at different scales and to prepare novel materials with unique physical and chemical properties. It is also a contact-free approach that makes it possible to work in inert or reactive liquid or gaseous environment. This leads today to a unique opportunity for designing, fabricating and even analyzing novel complex bio-systems. To illustrate this potential, in this paper, we gather our recent research on four types of laser-based methods relevant for nano-/micro-scale applications. First, we present and discuss pulsed laser ablation in liquid, exploited today for synthetizing ultraclean “bare” nanoparticles attractive for medicine and tissue engineering applications. Second, we discuss robust methods for rapid surface and bulk machining (subtractive manufacturing) at different scales by laser ablation. Among them, the microsphere-assisted laser surface engineering is detailed for its appropriateness to design structured substrates with hierarchically periodic patterns at nano-/micro-scale without chemical treatments. Third, we address the laser-induced forward transfer, a technology based on direct laser printing, to transfer and assemble a multitude of materials (additive structuring), including biological moiety without alteration of functionality. Finally, the fourth method is about chemical analysis: we present the potential of laser-induced breakdown spectroscopy, providing a unique tool for contact-free and space-resolved elemental analysis of organic materials. Overall, we present and discuss the prospect and complementarity of emerging reliable laser technologies, to address challenges in materials’ preparation relevant for the development of innovative multi-scale and multi-material platforms for bio-applications. MDPI 2021-03-12 /pmc/articles/PMC8001552/ /pubmed/33809072 http://dx.doi.org/10.3390/nano11030712 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ). |
spellingShingle | Review Al-Kattan, Ahmed Grojo, David Drouet, Christophe Mouskeftaras, Alexandros Delaporte, Philippe Casanova, Adrien Robin, Jérôme D. Magdinier, Frédérique Alloncle, Patricia Constantinescu, Catalin Motto-Ros, Vincent Hermann, Jörg Short-Pulse Lasers: A Versatile Tool in Creating Novel Nano-/Micro-Structures and Compositional Analysis for Healthcare and Wellbeing Challenges |
title | Short-Pulse Lasers: A Versatile Tool in Creating Novel Nano-/Micro-Structures and Compositional Analysis for Healthcare and Wellbeing Challenges |
title_full | Short-Pulse Lasers: A Versatile Tool in Creating Novel Nano-/Micro-Structures and Compositional Analysis for Healthcare and Wellbeing Challenges |
title_fullStr | Short-Pulse Lasers: A Versatile Tool in Creating Novel Nano-/Micro-Structures and Compositional Analysis for Healthcare and Wellbeing Challenges |
title_full_unstemmed | Short-Pulse Lasers: A Versatile Tool in Creating Novel Nano-/Micro-Structures and Compositional Analysis for Healthcare and Wellbeing Challenges |
title_short | Short-Pulse Lasers: A Versatile Tool in Creating Novel Nano-/Micro-Structures and Compositional Analysis for Healthcare and Wellbeing Challenges |
title_sort | short-pulse lasers: a versatile tool in creating novel nano-/micro-structures and compositional analysis for healthcare and wellbeing challenges |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001552/ https://www.ncbi.nlm.nih.gov/pubmed/33809072 http://dx.doi.org/10.3390/nano11030712 |
work_keys_str_mv | AT alkattanahmed shortpulselasersaversatiletoolincreatingnovelnanomicrostructuresandcompositionalanalysisforhealthcareandwellbeingchallenges AT grojodavid shortpulselasersaversatiletoolincreatingnovelnanomicrostructuresandcompositionalanalysisforhealthcareandwellbeingchallenges AT drouetchristophe shortpulselasersaversatiletoolincreatingnovelnanomicrostructuresandcompositionalanalysisforhealthcareandwellbeingchallenges AT mouskeftarasalexandros shortpulselasersaversatiletoolincreatingnovelnanomicrostructuresandcompositionalanalysisforhealthcareandwellbeingchallenges AT delaportephilippe shortpulselasersaversatiletoolincreatingnovelnanomicrostructuresandcompositionalanalysisforhealthcareandwellbeingchallenges AT casanovaadrien shortpulselasersaversatiletoolincreatingnovelnanomicrostructuresandcompositionalanalysisforhealthcareandwellbeingchallenges AT robinjeromed shortpulselasersaversatiletoolincreatingnovelnanomicrostructuresandcompositionalanalysisforhealthcareandwellbeingchallenges AT magdinierfrederique shortpulselasersaversatiletoolincreatingnovelnanomicrostructuresandcompositionalanalysisforhealthcareandwellbeingchallenges AT allonclepatricia shortpulselasersaversatiletoolincreatingnovelnanomicrostructuresandcompositionalanalysisforhealthcareandwellbeingchallenges AT constantinescucatalin shortpulselasersaversatiletoolincreatingnovelnanomicrostructuresandcompositionalanalysisforhealthcareandwellbeingchallenges AT mottorosvincent shortpulselasersaversatiletoolincreatingnovelnanomicrostructuresandcompositionalanalysisforhealthcareandwellbeingchallenges AT hermannjorg shortpulselasersaversatiletoolincreatingnovelnanomicrostructuresandcompositionalanalysisforhealthcareandwellbeingchallenges |