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Toward the Pathogenicity of the SLC26A4 p.C565Y Variant Using a Genetically Driven Mouse Model

Recessive variants of the SLC26A4 gene are globally a common cause of hearing impairment. In the past, cell lines and transgenic mice were widely used to investigate the pathogenicity associated with SLC26A4 variants. However, discrepancies in pathogenicity between humans and cell lines or transgeni...

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Detalles Bibliográficos
Autores principales:	Hu, Chin-Ju, Lu, Ying-Chang, Yang, Ting-Hua, Chan, Yen-Hui, Tsai, Cheng-Yu, Yu, I-Shing, Lin, Shu-Wha, Liu, Tien-Chen, Cheng, Yen-Fu, Wu, Chen-Chi, Hsu, Chuan-Jen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001573/ https://www.ncbi.nlm.nih.gov/pubmed/33801843 http://dx.doi.org/10.3390/ijms22062789

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