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Fate of β-Carotene within Loaded Delivery Systems in Food: State of Knowledge

Nanotechnology has opened new opportunities for delivering bioactive agents. Their physiochemical characteristics, i.e., small size, high surface area, unique composition, biocompatibility and biodegradability, make these nanomaterials an attractive tool for β-carotene delivery. Delivering β-caroten...

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Autores principales: Maurya, Vaibhav Kumar, Shakya, Amita, Aggarwal, Manjeet, Gothandam, Kodiveri Muthukaliannan, Bohn, Torsten, Pareek, Sunil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001630/
https://www.ncbi.nlm.nih.gov/pubmed/33802152
http://dx.doi.org/10.3390/antiox10030426
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author Maurya, Vaibhav Kumar
Shakya, Amita
Aggarwal, Manjeet
Gothandam, Kodiveri Muthukaliannan
Bohn, Torsten
Pareek, Sunil
author_facet Maurya, Vaibhav Kumar
Shakya, Amita
Aggarwal, Manjeet
Gothandam, Kodiveri Muthukaliannan
Bohn, Torsten
Pareek, Sunil
author_sort Maurya, Vaibhav Kumar
collection PubMed
description Nanotechnology has opened new opportunities for delivering bioactive agents. Their physiochemical characteristics, i.e., small size, high surface area, unique composition, biocompatibility and biodegradability, make these nanomaterials an attractive tool for β-carotene delivery. Delivering β-carotene through nanoparticles does not only improve its bioavailability/bioaccumulation in target tissues, but also lessens its sensitivity against environmental factors during processing. Regardless of these benefits, nanocarriers have some limitations, such as variations in sensory quality, modification of the food matrix, increasing costs, as well as limited consumer acceptance and regulatory challenges. This research area has rapidly evolved, with a plethora of innovative nanoengineered materials now being in use, including micelles, nano/microemulsions, liposomes, niosomes, solidlipid nanoparticles, nanostructured lipids and nanostructured carriers. These nanodelivery systems make conventional delivery systems appear archaic and promise better solubilization, protection during processing, improved shelf-life, higher bioavailability as well as controlled and targeted release. This review provides information on the state of knowledge on β-carotene nanodelivery systems adopted for developing functional foods, depicting their classifications, compositions, preparation methods, challenges, release and absorption of β-carotene in the gastrointestinal tract (GIT) and possible risks and future prospects.
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spelling pubmed-80016302021-03-28 Fate of β-Carotene within Loaded Delivery Systems in Food: State of Knowledge Maurya, Vaibhav Kumar Shakya, Amita Aggarwal, Manjeet Gothandam, Kodiveri Muthukaliannan Bohn, Torsten Pareek, Sunil Antioxidants (Basel) Review Nanotechnology has opened new opportunities for delivering bioactive agents. Their physiochemical characteristics, i.e., small size, high surface area, unique composition, biocompatibility and biodegradability, make these nanomaterials an attractive tool for β-carotene delivery. Delivering β-carotene through nanoparticles does not only improve its bioavailability/bioaccumulation in target tissues, but also lessens its sensitivity against environmental factors during processing. Regardless of these benefits, nanocarriers have some limitations, such as variations in sensory quality, modification of the food matrix, increasing costs, as well as limited consumer acceptance and regulatory challenges. This research area has rapidly evolved, with a plethora of innovative nanoengineered materials now being in use, including micelles, nano/microemulsions, liposomes, niosomes, solidlipid nanoparticles, nanostructured lipids and nanostructured carriers. These nanodelivery systems make conventional delivery systems appear archaic and promise better solubilization, protection during processing, improved shelf-life, higher bioavailability as well as controlled and targeted release. This review provides information on the state of knowledge on β-carotene nanodelivery systems adopted for developing functional foods, depicting their classifications, compositions, preparation methods, challenges, release and absorption of β-carotene in the gastrointestinal tract (GIT) and possible risks and future prospects. MDPI 2021-03-10 /pmc/articles/PMC8001630/ /pubmed/33802152 http://dx.doi.org/10.3390/antiox10030426 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ).
spellingShingle Review
Maurya, Vaibhav Kumar
Shakya, Amita
Aggarwal, Manjeet
Gothandam, Kodiveri Muthukaliannan
Bohn, Torsten
Pareek, Sunil
Fate of β-Carotene within Loaded Delivery Systems in Food: State of Knowledge
title Fate of β-Carotene within Loaded Delivery Systems in Food: State of Knowledge
title_full Fate of β-Carotene within Loaded Delivery Systems in Food: State of Knowledge
title_fullStr Fate of β-Carotene within Loaded Delivery Systems in Food: State of Knowledge
title_full_unstemmed Fate of β-Carotene within Loaded Delivery Systems in Food: State of Knowledge
title_short Fate of β-Carotene within Loaded Delivery Systems in Food: State of Knowledge
title_sort fate of β-carotene within loaded delivery systems in food: state of knowledge
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001630/
https://www.ncbi.nlm.nih.gov/pubmed/33802152
http://dx.doi.org/10.3390/antiox10030426
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