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Ocular Involvement of SARS-CoV-2 in a Polish Cohort of COVID-19-Positive Patients

The coronavirus SARS-CoV-2 responsible for the current human COVID-19 pandemic has shown tropism toward different organs with variable efficiency, eyes included. The purpose of this study has been to investigate the presence of detectable SARS-CoV-2 infection in ocular swabs in patients affected by...

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Autores principales: Dolar-Szczasny, Joanna, Toro, Mario D., Dworzańska, Anna, Wójtowicz, Tomasz, Korona-Glowniak, Izabela, Sawicki, Rafał, Boguszewska, Anastazja, Polz-Dacewicz, Małgorzata, Tomasiewicz, Krzysztof, Załuska, Wojciech, Rejdak, Robert, Bagnoli, Paola, Rusciano, Dario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001647/
https://www.ncbi.nlm.nih.gov/pubmed/33809199
http://dx.doi.org/10.3390/ijerph18062916
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author Dolar-Szczasny, Joanna
Toro, Mario D.
Dworzańska, Anna
Wójtowicz, Tomasz
Korona-Glowniak, Izabela
Sawicki, Rafał
Boguszewska, Anastazja
Polz-Dacewicz, Małgorzata
Tomasiewicz, Krzysztof
Załuska, Wojciech
Rejdak, Robert
Bagnoli, Paola
Rusciano, Dario
author_facet Dolar-Szczasny, Joanna
Toro, Mario D.
Dworzańska, Anna
Wójtowicz, Tomasz
Korona-Glowniak, Izabela
Sawicki, Rafał
Boguszewska, Anastazja
Polz-Dacewicz, Małgorzata
Tomasiewicz, Krzysztof
Załuska, Wojciech
Rejdak, Robert
Bagnoli, Paola
Rusciano, Dario
author_sort Dolar-Szczasny, Joanna
collection PubMed
description The coronavirus SARS-CoV-2 responsible for the current human COVID-19 pandemic has shown tropism toward different organs with variable efficiency, eyes included. The purpose of this study has been to investigate the presence of detectable SARS-CoV-2 infection in ocular swabs in patients affected by COVID-19. A consecutive series of 74 COVID-19-positive patients (age 21–89) were enrolled at two Polish COVID-19 hospitals for 4 months and were characterized by PCR for the presence of the SARS-CoV-2 genetic material in nasopharyngeal (NP) and ocular swabs, while their respiratory and ocular symptoms were noted. Almost 50% of them presented with severe/critical respiratory involvement, and some degree of eye disease. No tight correlation was observed between the presence of ocular and respiratory symptoms. Three male patients presenting with severe/critical lung disease tested positive in ocular swab, however with mild/moderate ocular symptoms. In conclusion, our study lends further support to the view that overt ocular infection by the SARS-CoV-2 virus is not such a frequent occurrence.
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spelling pubmed-80016472021-03-28 Ocular Involvement of SARS-CoV-2 in a Polish Cohort of COVID-19-Positive Patients Dolar-Szczasny, Joanna Toro, Mario D. Dworzańska, Anna Wójtowicz, Tomasz Korona-Glowniak, Izabela Sawicki, Rafał Boguszewska, Anastazja Polz-Dacewicz, Małgorzata Tomasiewicz, Krzysztof Załuska, Wojciech Rejdak, Robert Bagnoli, Paola Rusciano, Dario Int J Environ Res Public Health Article The coronavirus SARS-CoV-2 responsible for the current human COVID-19 pandemic has shown tropism toward different organs with variable efficiency, eyes included. The purpose of this study has been to investigate the presence of detectable SARS-CoV-2 infection in ocular swabs in patients affected by COVID-19. A consecutive series of 74 COVID-19-positive patients (age 21–89) were enrolled at two Polish COVID-19 hospitals for 4 months and were characterized by PCR for the presence of the SARS-CoV-2 genetic material in nasopharyngeal (NP) and ocular swabs, while their respiratory and ocular symptoms were noted. Almost 50% of them presented with severe/critical respiratory involvement, and some degree of eye disease. No tight correlation was observed between the presence of ocular and respiratory symptoms. Three male patients presenting with severe/critical lung disease tested positive in ocular swab, however with mild/moderate ocular symptoms. In conclusion, our study lends further support to the view that overt ocular infection by the SARS-CoV-2 virus is not such a frequent occurrence. MDPI 2021-03-12 /pmc/articles/PMC8001647/ /pubmed/33809199 http://dx.doi.org/10.3390/ijerph18062916 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Dolar-Szczasny, Joanna
Toro, Mario D.
Dworzańska, Anna
Wójtowicz, Tomasz
Korona-Glowniak, Izabela
Sawicki, Rafał
Boguszewska, Anastazja
Polz-Dacewicz, Małgorzata
Tomasiewicz, Krzysztof
Załuska, Wojciech
Rejdak, Robert
Bagnoli, Paola
Rusciano, Dario
Ocular Involvement of SARS-CoV-2 in a Polish Cohort of COVID-19-Positive Patients
title Ocular Involvement of SARS-CoV-2 in a Polish Cohort of COVID-19-Positive Patients
title_full Ocular Involvement of SARS-CoV-2 in a Polish Cohort of COVID-19-Positive Patients
title_fullStr Ocular Involvement of SARS-CoV-2 in a Polish Cohort of COVID-19-Positive Patients
title_full_unstemmed Ocular Involvement of SARS-CoV-2 in a Polish Cohort of COVID-19-Positive Patients
title_short Ocular Involvement of SARS-CoV-2 in a Polish Cohort of COVID-19-Positive Patients
title_sort ocular involvement of sars-cov-2 in a polish cohort of covid-19-positive patients
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001647/
https://www.ncbi.nlm.nih.gov/pubmed/33809199
http://dx.doi.org/10.3390/ijerph18062916
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