A Holistic Evolutionary and 3D Pharmacophore Modelling Study Provides Insights into the Metabolism, Function, and Substrate Selectivity of the Human Monocarboxylate Transporter 4 (hMCT4)

Monocarboxylate transporters (MCTs) are of great research interest for their role in cancer cell metabolism and their potential ability to transport pharmacologically relevant compounds across the membrane. Each member of the MCT family could potentially provide novel therapeutic approaches to vario...

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Detalles Bibliográficos
Autores principales: Papakonstantinou, Eleni, Vlachakis, Dimitrios, Thireou, Trias, Vlachoyiannopoulos, Panayiotis G., Eliopoulos, Elias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001682/
https://www.ncbi.nlm.nih.gov/pubmed/33805725
http://dx.doi.org/10.3390/ijms22062918

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