The Picornavirus Precursor 3CD Has Different Conformational Dynamics Compared to 3C(pro) and 3D(pol) in Functionally Relevant Regions

Viruses have evolved numerous strategies to maximize the use of their limited genetic material, including proteolytic cleavage of polyproteins to yield products with different functions. The poliovirus polyprotein 3CD is involved in important protein-protein, protein-RNA and protein-lipid interactio...

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Detalles Bibliográficos
Autores principales: Winston, Dennis S., Boehr, David D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001691/
https://www.ncbi.nlm.nih.gov/pubmed/33803479
http://dx.doi.org/10.3390/v13030442

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