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Deficiency of Lipin2 Results in Enhanced NF-κB Signaling and Osteoclast Formation in RAW-D Murine Macrophages
Lipin2 is a phosphatidate phosphatase that plays critical roles in fat homeostasis. Alterations in Lpin2, which encodes lipin2, cause the autoinflammatory bone disorder Majeed syndrome. Lipin2 limits lipopolysaccharide (LPS)-induced inflammatory responses in macrophages. However, little is known abo...
Autores principales: | Watahiki, Asami, Hoshikawa, Seira, Chiba, Mitsuki, Egusa, Hiroshi, Fukumoto, Satoshi, Inuzuka, Hiroyuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001760/ https://www.ncbi.nlm.nih.gov/pubmed/33809261 http://dx.doi.org/10.3390/ijms22062893 |
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