Heterogeneous Off-Target Effects of Ultra-Low Dose Dimethyl Sulfoxide (DMSO) on Targetable Signaling Events in Lung Cancer In Vitro Models

Targetable alterations in cancer offer novel opportunities to the drug discovery process. However, pre-clinical testing often requires solubilization of these drugs in cosolvents like dimethyl sulfoxide (DMSO). Using a panel of cell lines commonly used for in vitro drug screening and pre-clinical te...

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Detalles Bibliográficos
Autores principales: Baldelli, Elisa, Subramanian, Mahalakshmi, Alsubaie, Abduljalil M., Oldaker, Guy, Emelianenko, Maria, El Gazzah, Emna, Baglivo, Sara, Hodge, Kimberley A., Bianconi, Fortunato, Ludovini, Vienna, Crino’, Lucio, Petricoin, Emanuel F., Pierobon, Mariaelena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001778/
https://www.ncbi.nlm.nih.gov/pubmed/33802212
http://dx.doi.org/10.3390/ijms22062819

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001778/
https://www.ncbi.nlm.nih.gov/pubmed/33802212
http://dx.doi.org/10.3390/ijms22062819

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